PPT-Transfusion dependent microcytic hypochromic anemia with low ferritin

Dr Babak Abdolkarimi Pediatric hematologist Case presentation A 8 y girl with hypochromic microcytic anemia and regular tranfusion dependency since age 2 y and frequent low Ferritin level . Introduction. Iron is an essential nutrient needed by every human cell. Iron deficiency is the most common deficiency disease worldwide. More than one billion people have iron deficiency and about 700 million people have iron deficiency . Anemia:. Deficiency of hemoglobin in the blood.. Causes: . Too few RBCs.. Too little hemoglobin in cells. Decreased packed cell volume.. This may be due to. :. decreased production of RBCs.. increased destruction.. Mohammad Asgar Khan, MD. Anemia. Learning Objectives:. Learn the pathophysiology of anemia in CKD.. Learn the diagnostic challenges of anemia in CKD.. Learn the therapeutic strategies and related controversies in the treatment of anemia in CKD.. range. The normal range varies with age, so anaemia. can be defined as:. • Neonate: Hb <14 g/dl. • 1–12 months: Hb <10 g/dl. • 1–12 years: Hb <11 g/dl.. Physiologic Anemia of the Newborn. . ANEMIAS. Done by: Mohammad Saleh. Mosab Abu . Shqeer. Hamza . Alhamdan. Definition. A decrease in hemoglobin ( . Hb. ) , hematocrit ( . Hct. ) , or RBC count.. Measurement. Men. Women. Hemog. l. obin (g/dL). Objectives. Describe the physiology of oxygen delivery. List risks and benefits of red blood cell transfusions. Discuss the evidence regarding thresholds for red blood cell transfusion. Explain methods to prevent the need for intra- and post-operative transfusions. April 12, 2014. Virginia Harrod, MD, PhD. Pediatric Hematology Oncology. Overview . Definition of anemia. Review of CBC values. Review of Hemoglobin. Types of Anemia. Microcytic, macrocytic, normocytic. Anemia . Rand . Al-shayeb. Step up to medicine. Davidson's Principles and Practice of Medicine. Diagnosing the cause of anemia. If . microcytic anemia (MCV<80), the differential diagnosis includes the following. Abeer. . Anwer. Ahmed. Objectives. Explain background, definition . and etiology of . hypochromic. . anemias. Outline diagnostic algorithm of . . hypochromic. . anemias. Identify key laboratory findings to diagnose . Key wordsAnaemia, hypochromic microcytic; Erythrocyte indices; Haemoglobin H disease; Mean corpuscularvolume; Thalassaemia, beta Children's Haematology and Cancer Centre, Mount ElizabethHospital, L 1 Hypochromic microcytic anemia with iron overload Description Hypochromic microcytic anemia with iron overload is a condition that impairs the normal transport of iron in cells. Iron is an essential Levels Of Anemia• Hemoglobinlessthan11• Hemoglobinlesthan9:Moderate• Hemoglobinlessthan7:Severe Hypoxia• LowPO2• OxygenContent=Hemoglobin+PO2• Acutesigns/symptoms:• COLLEGE OF MEDICINE. DEPARTMENT OF PATHOLOGY AND FORENSIC. Medicine. Dr. . Ala’a. . A.Razak. . Abood. Iraqi Board of . Haematopathology. Objectives. :. 1- Define microcytic anemia and give differential diagnosis of microcytosis.. Allogenic. HSCT . in Congenital Sideroblastic Anemia. . Etiology : Production , Destruction , Blood Loss. SIZE. in CLASSIFICATION OF ANEMA. . Classification of MICROCYTIC ANEMIA. Sideroblastic.