269 flammation Cardiovascular disease EndotheliumIntroductionNAFLD with obesity type 2 diabetes andNAFLD is still not clear even if the insulin In particular a decreased sensi Moreover a lar ID: 959944
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269 Metabolic syndrome, Non-alcoholic fatty liver dis-ease, Non-alcoholic steatohepatitis, Atherosclerosis, In- flammation, Cardiovascular disease, Endothelium.IntroductionNAFLD with obesity, type 2 diabetes andNAFLD is still not clear, even if the insulin. In particular, a decreased sensi-. Moreover, a large body ofNonalcoholic fatty liver di-NAFLD with obesity, type 2 diabetes and hy-syndrome (MS), including NAFLD, obesity,central fat distribution, diabetes, dyslipidemia,dial infarction, stroke or both. In a prospectiveout CVD or diabetes at baseline, Lakkais associated with anincreased risk of CVD and all-cause mortality.logical point of
view, growing evidences impli-mation process evidentiated in these patients A. FORGIONE*, M.A. ZOCCO*, A. LUPASCU*, A. DI GIORGIO*, R. FLORE, POLA, G. GASBARRINI, A. GASBARRINI, P. TONDI, A. GRIECO* 270 . Recentely, Bugianesi et al con-Metabolic Syndrome and including NAFLD, obesity, central fat distri-and all-cause mortality. Another population-In particular, changes in the atherosclerosis40% were higher in patients with MS than in. Interestingly,by conside-. Finally, a. Moreover, theadipose tissue pro-duce and or influence the action of many,C-reactive protein (CRP) in the liver. TheMS, as evaluated in 14719 apparently healthyMoreover,pa
tients is initiated at the endothelial level,stressing the key role of this active and dy-namic tissue in the pathophysiological path-ways of these patients. In particular, it is in-A. Santoliquido, C. Di Campli, L. Miele, M.L. Gabrieli, A. Forgione, M.A. Zocco, A. Lupascu, et al. effect that can be prevented by vitamin C.atherosclerosis, and, consequently, betweenReferencesY, YABATEP, AP, resistance: a cause-effect relationship? Dig LivASTALDELLIINOMIYAJK, LÕIMH, Wtion Survey. Circulation, 2004; 109: 42-46.TA, J, et al.bolic syndrome. Diabetes Care 2003; 26: 1251-VANY, B11)EEDWANIAIFAIrioscler Thromb Vasc Biol 2005; 25-193-197.G, CS,et al.