PPT-1 Role of Molecular Phylogenetics in Studying

Disease Epidemiology and Evolution Jyotsana Dixit Praveen Karanth Lab 2 Molecular Phylogenetics and Infectious diseases Evaluation of pathways of transmission among several hosts and polarity of transmission events. Over the past decade an ever growing arsenal of techniques has helped researchers dissect the innermost secrets of the cell and develop new ways to detect and attack disease These techniques also have been used to produce vast amounts of once rare d Diffusion plus Convection. ).  . Molecular Diffusion in Gases. Equimolar. . Counterdiffusion. A. B. B. A.  .  . In terms of mole fraction, . Molecular Diffusion in Gases. Uni. -component Diffusion. Methods and applications. Divya. B.. PK. lab, . CES. , . IISc. Quantifying species diversity. Captures evolutionary history. Uses molecular data – DNA sequence. Workshop on Molecular Phylogenetics 2014, IISc. Damjan. . Temelkovski. Dr.. . Tamas. Kiss. Dr.. Gabor . Terstyanszky. University of Westminster. Molecular Docking. a.k.a. . in-. silico. docking. Simulating the interaction between two molecules: . Chapter 9. Molecular Shapes. Section 9.1. Lewis structures only provide a 2-D representation of a molecule. However, by including the bond angles of molecules, a more accurate 3-D representation can be achieved. Spring . 2014. “Problems” with morphological. data…. Convergence and parallelisms. Reduction and character loss. Phenotypic vs. genotypic differences. Evaluation of homology. Misinterpretation of change or polarity. MOLECULAR BIOLOGY TECHNIQUES II.. Polymerase Chain Reacton – PCR. DNA sequencing. Amplification of specific DNA fragments. MOLECULAR BIOLOGY – PCR. Cloning and/ or isolation from a genomic library . ARTICLE IN PRESS Please cite this article in press as: Calvi Denise Chac. 10 October 2014. Immunology. The study of the human immune system . Lymphocytes. B Cells. Membrane bound antibody. Activation: bind to pathogen and triggered by helper T cells. MHC II proteins present antigen peptide on cell surface. Spring . 2012. “Problems” with morphological. data…. Convergence and parallelisms. Reduction and character loss. Phenotypic vs. genotypic differences. Evaluation of homology. Misinterpretation of change or polarity. Chemistry GT 3/20/15. Drill. Calculate the percent composition of Na. 2. SO. 4. .. HW: Molecular Formula WS (pg. 4). MM. =142.05 . g. /mol. 32.37% Na, 22.58% S, 45.05% O. Chem. Joke of the Day. The photon checked into a hotel. What did it say when the bellhop asked for its bag?. IAMZ 2015 . Patrick Hayes. Dept. Crop and Soil Science. Oregon State University. Corvallis, Oregon USA. www.barleyworld.org. Class Outline. General considerations for molecular breeding. Selection tools and molecular breeding . MMPBSA. D. G. free. D. G. bound. (1) Use free energy perturbation methods to estimate relative free energies. . DD. G =. D. G. free. - . D. G. bound. how to estimate free energies?. D. G?. ?. (2) Estimate potential of mean force along pathway? (but, what. ;. . the. . study of . biology. at the . molecular. level.. Molecular biology. ;. . the. . study of . gene . structure and functions at the . molecular level. . to understand the molecular basis of hereditary, genetic variation, and the expression patterns of genes. .