PPT-Lipids III: Plasma Lipoproteins

Learning Objectives The structure and composition of lipoproteins Exogenous dietary fat transport vs endogenous fat transport systems Key enzymes involved in lipoprotein metabolism Key cholesterol transporting lipoproteins and the relationship between their concentrations and the incidence of cardiovascular diseases. Lipids are….. It can be defined as . nonpolar. organic compound insoluble in polar solvent , but . soluble in organic solvents. such as benzene ,ether, . chloroform.. Biological role of lipids. :. Lipids. Essential . macronutrients. Provide . energy. Building blocks for cell membranes. Form many important hormones. Help transport fat-soluble nutrients. Contribute to flavor and texture of . food. Dr. Huda Hania. Lipid chemistry . Lipid chemistry . Definition . Fats and Oils (triglyceride) . Waxes. Steroids. Fat- soluble vitamins. Phospholipid. Mono- di glycerides . Lipid compounds including: . Fats and Oils. Classification of Nutrients. Carbohydrates. Lipids. – . 9 calories per gram. Protein. Vitamins. Minerals. Water. LIPIDS. Most . concentrated. source of food energy. Provide . Nature’s flavor enhancer. lipids vs carbohydrates. - . both . Contain: carbon. , hydrogen, and . oxygen. LIPIDS do not:. dissolve in water. provide structure to food products. lipids. Food Examples: . 3.4 What Are Lipids?. Lipids. are a diverse group of molecules that contain regions composed almost entirely of hydrogen and carbon. All lipids contain large chains of nonpolar hydrocarbons. Most lipids are therefore hydrophobic and water insoluble. Pratt & . Cornely. , . Ch. 8. Lipids and Membranes. There is a lot of important biochemistry of lipids.. We won’t cover it all!. The key points for this class have to do with their role in membranes and fat metabolism. CHAPTER 10. UNIT. TARGETS. DESCRIBE THE MOLECULAR STRUCTURE 3 types of lipids: GLYCERIDES, PHOSHOLIPIDS, AND STEROLS. DEFINE SATURATED, MONOSATURATED AND POLYUNSATURATED FATTY ACIDS.. LIST CATEGORIES OF LIPIDS BASED ON PHYSICAL STATE AND DIETARY SOURCES. Plasma lipids . 200 . Lipoproteins . 201 . Fatty acids . 200 . Disorders of lipid metabolism . 207 . Cholesterol . 201 . Investigation of hyperlipidaemias . 214 . FATTY ACIDS . Lipids play a critical role in almost all aspects of . Glycrophospholipids degradation . Lipoproteins. G. L. Y. C. E. R. O. L. FATTY ACID. FATTY ACID. PHOSPHOACYLGLYCEROL. PHOSPHATE. ALCOHOL. Again this is the representation structure of glycerophospholipids.. . very importance to . medical practice owing to its strong relations to . Arteriosclerosis and thus obesity, HTN, DM and . other abnormalities . . Good prognosis in the . manegment. of these conditions are . Prof. Mamoun Ahram. Resources. This lecture. Lippincott’s Biochemistry, Ch. 15. What are lipids?. Lipids are heterogeneous, hydrophobic, compartmentalized in membranes, as droplets of triacylglycerol (TAG), or in lipoprotein (LP) particles or, or protein-bound. . They bind with . soluble . protein. complexes . called. . lipoproteins. Lipids . can . be derived from food (exogenous) or synthesized. in the body (endogenous). The water-soluble (polar). groups of proteins, phospholipids and free cholesterol. Main lipids in the blood are the triglycerides and cholesterol.. Insoluble in the water.. Transport in the blood is via lipoproteins. Triglycerides. Glycerol with 3 attached fatty acids. Exogenous source : Dietary.