PPT-Hormone, Calcitonin, Calcium and Phosphate

MetabolismVitamin D Bone and Teeth Dr Noori M Luaibi Hormone Calcitonin Calcium and Phosphate MetabolismVitamin D Bone and Teeth The physiology of calcium and phosphate metabolism formation of bone and teeth and regulation of . Mary, Larry, and Melinda . Anatomy of The Skeletal system . -“Skeleton . can be defined as the hard framework of human body around which the entire body is built. Almost all the hard parts of human body are components of human skeletal system. Joints are very important because they make the hard and rigid skeleton allow different types of movements at different locations. If the skeleton were without joints, no movement would have taken place and the significance of human body; no more than a stone. Outline. . Key players of Calcium hemostasis. Parathyroid hormones ( Function, Regulation, Pathophysiology). Vit D. Calcium. Calcitonin. PTH . Anatomy (briefly). Importance of Ca and its percentage in blood. calcium, normally at a concentration of around 10 mg/. dL. (5 . mEq. /L, 2.5 . mmol. /L), is partly bound to protein and partly diffusible. The calcium in the plasma is present in three forms: . (1) About . Calcium Physiology. Functions and daily requirements. Critical to the function of the skeletal, nervous, muscular, and cardiovascular systems. Body stores. More than 98% stored in the bones. Total serum calcium = 10 mg/dL. Carbohydrates. Lipids. Proteins. Vitamins. Minerals. . macroelements. , . microelements . Roughage . Wate. r . Classification of dietary elements. In addition to four ‘foundation elements’ C, H, N , O that are normal components of bio-organic molecules ( carbohydrates, proteins, fats, nucleic acids) . Biochemistry of the Parathyroid Glands & Ca. +2. homeostasis. Calcium metabolism. Most . abundant mineral in the human body. Total . Calcium in the . human body is about 1 to 1.5 kg, 99% of which . maintain the body's . calcium. . level within a very narrow range, so that the . nervous. and . muscular systems. can function properly.. Parathyroid glands control the calcium in our bodies--how much calcium is in our bones, and how much calcium is in our blood. Calcium is the most important element in our bodies (we use it to control many systems), so calcium is regulated very carefully. Parathyroid glands control the . It is provided in sterile solution for subcutaneous or intramuscular injection. Each milliliter contains: calcitonin-salmon 200 I.U., acetic acid, USP, 2.25 mg; phenol, USP, 5.0 mg; sodium acetate tri status testing F ormulary Working Group Laboratory Medicine Program Eastern Health . 1J442 , Health Sciences Centre, 300 Prince Philip Drive, , NL A1B 3V6 Office: 709 777 - 6375 Fax : 709 - 777 2442 E erogeneous nucleation, is also inhibited by urinary citrate. All these properties of citrate Urinary Citrate in Kidney Stone DiseaseYukio USUI, Shouji MATSUZAKI, Kazuo MATSUSHITA and Masanori SHIMA D Lec 9 and 10. Distribution . Different Forms of Calcium. M. ost of the calcium in the body exists as the mineral hydroxyapatite, Ca. 10. (PO. 4. ). 6. (OH). 2. .. . Calcium in the plasma: . . . 45% in ionized form (the physiologically active form). The metabolic roles of calcium and phosphorus in energy metabolism, signal transduction, and the formation and turnover of bone; . Calcium and phosphate homeostasis and affecting factors; and . Disorders of calcium and phosphorus homeostasis. two. pairs of glands usually positioned behind the left and right lobes of the . thyroid. . Each gland is a . yellowish. -. brown . flat ovoid that resembles a lentil seed, usually about . 6. mm long and . DISORDERS OF THE PARATHYROID GLANDS:. DISORDERS OF THE PARATHYROID GLANDS. Disorders of the Parathyroid Glands:. Disorders of the Parathyroid Glands Maintenance of calcium, phosphate and magnesium homeostasis is under the influence of two polypeptide hormones; parathyroid hormone(PTH), and .