PPT-Calcium metabolism and its regulation

Lec 9 and 10 Distribution Different Forms of Calcium M ost of the calcium in the body exists as the mineral hydroxyapatite Ca 10 PO 4 6 OH 2 Calcium in the plasma 45 in ionized form the physiologically active form. Pratt and . Cornely. Chapter 19. Regulation by Compartmentalization. Form of . reciprocal . regulation. Degradation vs biosynthesis. Requires transporters. Specialization of organs. Fuel Storage. Total amounts. Pratt and . Cornely. Chapter 19. Regulation by Compartmentalization. Form of reciprocal regulation. Degradation vs biosynthesis. Requires transporters. Specialization of organs. Fuel Storage. Fuel Usage: About 7000 kJ/day minimum. Dr Anissa Atif Mirza. What is Metabolism?. Metabolism is a . network of metabolic /biochemical reactions.. Carried out in living cells.. In a. well organized, integrated and regulated manner.. Related to various biomolecules viz. Outline. . Key players of Calcium hemostasis. Parathyroid hormones ( Function, Regulation, Pathophysiology). Vit D. Calcium. Calcitonin. PTH . Anatomy (briefly). Importance of Ca and its percentage in blood. Hypercalcemia. Steven Chessler, MD, Ph.D.. March, 2015. Internal Medicine noon conference. (F5). History and Physical. A 45 year-old female consults you because of . a low bone mineral density (BMD). She relates that she . Dr.F.Iranmanesh. Calcium,Physiologic. chemistry. Distribution:. 5. th. most common element. Most prevalent . cation. in the body. Healthy adult contain 1-1.3kg of calcim,99% in the form of hydroxyapatite,1% in ECF & Soft tissue. Disorders During Pregnancy. Dr. . Mitra. . Niafar. Professor of Endocrinology and Metabolism. Tabriz University of Medical Sciences. Pregnancy and . Ca. -P . homeostasis. Pregnancy is associated with substantial changes in calcium-phosphate homeostasis, resulting from . Carbohydrates. Lipids. Proteins. Vitamins. Minerals. . macroelements. , . microelements . Roughage . Wate. r . Classification of dietary elements. In addition to four ‘foundation elements’ C, H, N , O that are normal components of bio-organic molecules ( carbohydrates, proteins, fats, nucleic acids) . By Josephine Abraham, Dev Abraham . Calcium Homeostasis. Serum calcium maintained at a constant level. Cellular & tissue effects of calcium depend on blood calcium maintenance within a specific range.. BC 2.5 Microbiology and Genetics 12 2 6 85 BC 2.6 Quantitative Analysis and Molecular Biology 12 2 6 85 BC 2.7 Viva-Voce -- 1 25 ----- Total marks The metabolic roles of calcium and phosphorus in energy metabolism, signal transduction, and the formation and turnover of bone; . Calcium and phosphate homeostasis and affecting factors; and . Disorders of calcium and phosphorus homeostasis. Regulation of bone remodelling.. Osteoporosis.. MUDr. Miroslava Hlaváčová. , PhD.. Department of Biochemistry . Faculty of Medicine, Masaryk University. Calcium in the body:. the whole calcium . 1.0 – 1.3 kg. Primary . Hyperparathyroidism. 99% of total body calcium in the bone . 1% in ICF ,ECF , cell membranes *. * 50% ionized . 40% bound to albumin. . 10% citrate, phosphate. Ian de Boer, MD, MS. Associate Professor of Medicine. Adjunct Associate Professor of Epidemiology. Division of Nephrology & Kidney Research Institute. University of Washington. Many investigators have contributed to this work.