PPT-Population genetics Dr Gavin Band

Wellcome Trust Advanced Courses Genomic Epidemiology in Africa 21 st 26 th June 2015 Africa Centre for Health and Population Studies University of KwaZuluNatal Durban South Africa. Beaumont 1 Wenyang Zhang and David J Balding School of Animal and Microbial Sciences The University of Reading Whiteknights Reading RG6 6AJ United Kingdom Institute of Mathematics and Statistics University of Kent Canterbury Kent CT2 7NF United King and . admixture . among . human populations . Katarzyna. Bryc. OEB 275br. February 19, 2013. Outline. The field of population genetics. Learning about human history from genetics. Out of Africa settlement of continents. Contact: Gavin Hepp Webfoot Painting Co gavin@webfootpainting.com (541) 390 - 0590 P ROMINENT L OCAL P AINTING C OMPANY S TARTS 2010 ON THE R IGHT “F OOT ” Webfoot Painting to Donate $ Judy H. Cho, M.D. . Ward-Coleman Professor of Medicine and Genetics, Icahn School of Medicine at Mount Sinai. Central importance of human genetics. Germline. DNA variants.  disease susceptibility. -----. Module . 11 . – . Association Genetics. Nicholas Wheeler & David Harry – Oregon State University. What is association genetics?. Association genetics is the process of identifying alleles that are disproportionately represented among individuals with different phenotypes. It is a population-based survey used to identify relationships between genetic markers and phenotypic traits. direct extension of Mendel’s laws, molecular genetics, and the ideas of Darwin. Instead of genetic transmission between individuals, population genetics considers the gene transmission at the population level. Objectives. Identify. traits that vary in populations and that may be studied.. Explain. the importance of the bell curve to population genetics.. Compare . three causes of genetic variation in a population.. Pre-Class Exercise . Learning Objectives. By the end of this session, students should be able to…. Illustrate how historical human migration patterns have contributed to genetic variation observed in modern populations.. Gene. Allele. Population. Gene . pool. Population Genetics. Starter - write biological definitions for the following key words:. Gene – a section of DNA that codes for a particular . protein/polypeptide. is concerned with the question of whether a particular allele or genotype will become more common or less common over time in a population, and Why.. Example: . Given that the CCR5-. D. 32 allele confers immunity to HIV, will it become more frequent in the human population over time?. Population genetics. : focuses on genetic changes within an interbreeding population.. Gene pool = _______________________________. Allele Frequency . =. all the genes in a population . Shows frequency of . What is Population Genetics?. Describes allele and genotype frequencies in populations over space and time. Models evolutionary forces (survival, mutation, migration, etc.). Models are generally limited to one or a few loci. Institute of Zoology, . Chinese Academy of Sciences, Beijing, China. Oct 2018. University of Science and Technology of China. 2017.6-2018.6. 2013.9-2018.6. A short self-introduction. USTC, School of Life Science, BS. 4. Population and Evolutionary Genetics. lachance.joseph@gmail.com. https://. popgen.gatech.edu. /. COMT. (. catechol-O-methyltransferase. ) and test-taking anxiety. What is wrong with this claim?. Case Study #1.