PURPOSE / OBJECTIVE(s) RESULTS

The use of proton therapy PT for partial breast irradiation PBI in early stage breast cancer is an area of active investigation Proton PBI has the potential for decreased morbidity versus photon PBI because of superior sparing of surrounding normal breast tissue and underlying thoracic structures with protons Figure 1 To date singleinstitutional studies have reported the feasibility of proton PBI but have resulted in conflicting results on toxicities with some publications showing suboptimal cosmetic outcomes Table 1 Herein we report 3year outcomes of a prospective phase II trial investigating the efficacy toxicity and cosmetic outcomes of proton PBI

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