PPT-Antibodies, BiTEs , and CARs: the new ABC’s of Myeloma Therapy

Author : aaron | Published Date : 2020-04-04

June 6 2019 Adam D Cohen MD Director Myeloma Immunotherapy Assistant Professor Medicine Abramson Cancer Center University of Pennsylvania Outline Background Antibodies

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Antibodies, BiTEs , and CARs: the new ABC’s of Myeloma Therapy: Transcript

June 6 2019 Adam D Cohen MD Director Myeloma Immunotherapy Assistant Professor Medicine Abramson Cancer Center University of Pennsylvania Outline Background Antibodies and antibodydrug conjugates. 9 FM 955 FM 939 FM 931 FM Almaden 64 1065 FM 1045 FM Alpha 1057 FM 1073 FM Aramac 1079 FM Atherton 67 720 AM Augathella 11 9a 1077 FM Aurukun 1029 FM Ayr 62 Ayton 62 1039 FM 1071 FM Babinda 42 957 FM 941 FM Ballera 56 1059 FM 1043 FM 1027 FM Bancroft What is smouldering myeloma? Smouldering myeloma (also known as asymptomatic myeloma) is a veryslow-growing type of myeloma. Myeloma, also known as multiple myeloma, is a type of bone marrow cancerari Dr. Andrew Chantry. Senior Clinical Lecturer and Honorary Consultant in . Haematology. University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust. UKMF Autumn Educational Day ‘The evolving management of multiple myeloma and related plasma cell disorders’. Ready for Prime Time?. DANA-FARBER . CANCER INSTITUTE. Nikhil C. Munshi, MD . Professor of Medicine . Harvard Medical School. Boston VA Healthcare System. Director . Basic and Correlative Sciences. Dana-Farber Cancer . Reported by . Ganesh . M.Sc.D. . endo. student. What is immunoglobulin ?. Immunoglobulin's . are glycoprotein molecules that are produced by plasma cells in response to an immunogen and which function as antibodies. The . new treatment in the horizon. Dr Amin . I. slam . MB, MRCP UK , FRCPath UK. Consultant haematologist and . H. aemato. -Oncologist. Southend University Hospital NHS Foundation trust. Myeloma patients support group meeting. Program Goals. Defining Multiple Myeloma. Case 1. Diagnostic Criteria. Multiple Myeloma Requiring Therapy. Cytogenetic Risk Features. Case 1 (cont). Newly Diagnosed Multiple Myeloma. NCCN. ®. . Therapy for Transplant-Eligible Patients. Copenhagen. , . June 11. th. . 2016. EU Drug Approval and Reimbursement Policy. No standardized. cost-benefit formula exists across the EU. . The Estonian reimbursement committee (Estonian Health Foundation) initially (2013) . Smoldering Myeloma: To Treat or not to Treat Ruben Niesvizky MD Myeloma Center Myelomacenter.org run9001@med.cornell.edu CASE A 47-year-old man is diagnosed with smoldering multiple myeloma . He has Pritesh Patel, MD. OVErview. Disease overview. How I approach initial treatment. Treatment considerations at relapse. ≈96,000. MM patients. How many people are affected by myeloma?. National Cancer Institute Survival Epidemiology and End Results Program SEER Cancer Statistics Review 1975-2012. Available at . cyclin. and PI3k pathways. UKMF Spring meeting 2015. Kwee Yong, UCL Cancer Institute. Not one, but many myelomas. Dysregulation. of D-type . cyclin. in multiple myeloma. Early oncogenic events . dysregulate. Vi Dao, MD, FRCPC. vdao@cancercare.mb.ca. Presenter Disclosure. Faculty: Vi Dao. Relationships with commercial interests: none. Mitigating Potential Bias. Not Applicable. Learning Objectives. Distinguish MGUS from multiple myeloma. Can we do better?. [Hospital name]. [Date]. What is myeloma?. Cancer of plasma cells. Leads to:. Bone infiltration. - fractures (especially vertebral wedge fractures), hypercalcaemia. - pain. [Hospital]. [date]. Myeloma: Symptoms to diagnosis . Can we do better?.

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