PPT-Summary of Immune Response Questions

Case 4 week 3 Brian Black Objectives What are the signs and symptoms of mastitis Which body system is effected How is the normal physiological functioning of this area of the body been disturbed by the infection. Zoran . Galic. Ph.D. .. Division of Hematology/Oncology. David Geffen School of Medicine UCLA. zgalic@ucla.edu. August . 11, 2015. In response to pathogens, vertebrate immune systems use two interconnected systems:. THE IMMUNE SYSTEM. NONSPECIFIC DEFENSES AGAINST INFECTION INCLUDE THE. SKIN. MUCOUS MEMBRANES. PHAGOCYTIC CELLS. ANTIMICROBIAL PROTEINS. THE IMMUNE SYSTEM. NONSPECIFIC DEFENSE MEANS THAT THEY DON’T DISTINGUISH BETWEEN MICROBES. Department of . Immunology. IMMU 7070-Introductory Immunology 2010-2011. Dr. . Nyla . Dil. 437 Apotex Centre. 272-3149. Oct 20, 2011. Objectives. . To understand how the immune system performs its major physiologic function.. PATH 417A. Jen Yong. Case. : . Food-borne bacterial infection. “One Too Many Hamburgers”. 10-year-old Ronnie McDonald has developed . abdominal cramps. , . bloody diarrhea. and a . low grade fever. Kuby. . Immunology. , . 7e: Chapter 1. A historical perspective of immunology. What is immunity?. Immunity is the state of protection against foreign pathogens or substances (antigens). Latin term . LYMPHOCYTES. Are the key cells of the immune system. Two types: B and T. Both produced in the bone marrow. B matures in the bone marrow. T matures in the thymus. Immunocompetency. B and T lymphocytes must recognize “self.”. HIV. (Human immunodeficiency virus)- a virus that attacks the immune system.. Infection with HIV can be prevented. Responsible decisions is the most valuable tool for protection against HIV.. Example: Abstinence from sexual activity and injecting drugs reduce your risk.. Chapter 4. Introduction. Molecules recognized as “non-self” are antigens. Several mechanisms to protect itself . First level of protection include physical and biochemical-skin, acid in stomach. Second level of protection phagocytic cells, enzymes, and proteins. Maria Bleier . PATH 417. Overview. The Case. 10 . yr. old male patient . Ronnie McDonald.. Developed abdominal cramps, bloody diarrhea and low grade fever. Physician’s examination: . Asks about history in terms of food consumed – undercooked hamburgers from previous weekend as prime suspect. By: Dr. Suzan Y.. SPECIFIC COMPONENTS OF IMMUNE SYSTEM: LYMPHOCYTES. B-Lymphocytes (“B cells”). T- Lymphocytes (“T cells”). Natural Killer Cells (NK cells). Memory Cells. Suppressor Cells. They have different functions in specific immunity. The Immune System. The immune system is a group of cells & soluble molecules, which interact & distinguish patterns in the body as “self” or “non-self,” in order to eliminate those that are “non-self.”. CfE. . Advanced Higher Biology. Unit . 2: . Organisms and Evolution. If you have done Higher Human Biology this is just revision!!! Use the key areas to create revision notes!. HOMEWORK: ACTIVITY G – Self Study Task – Immune response to parasites. Immunological unresponsiveness to self is referred to as . tolerance. or . self-tolerance. Very important to human health. How is this achieved?. -cells with receptors for self-antigens are destroyed in the thymus or bone marrow (central tolerance). infections. Lec. . 3. The relationship between viruses and the immune system is much more intimate than it is for most bacteria: viruses often modify the cells within which they replicate, thereby rendering them ‘foreign’ and susceptible to attack by sensitized lymphocytes; furthermore, .