PPT-Immune Response Innate Immune Response

The Immune System The immune system is a group of cells amp soluble molecules which interact amp distinguish patterns in the body as self or nonself in order to eliminate those that are nonself. Zoran . Galic. Ph.D. .. Division of Hematology/Oncology. David Geffen School of Medicine UCLA. zgalic@ucla.edu. August . 11, 2015. In response to pathogens, vertebrate immune systems use two interconnected systems:. non-AIDS Morbidity. Peter W. Hunt, MD. Associate Professor of Medicine. UCSF HIV/AIDS Division. A shift in focus…. T cell activation as a target for interventions in the pre-ART era. Monocyte activation and inflammation a target during treated HIV disease. Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. Present before exposure to pathogens. Present at birth. Non-antigen specific. Consists of:. Skin… barrier for microbes and viruses. Compromised by abrasion or laceration. Sebacious. sweat is acidic (pH 3-5)… prevents colonization of bacteria. Department of . Immunology. IMMU 7070-Introductory Immunology 2010-2011. Dr. . Nyla . Dil. 437 Apotex Centre. 272-3149. Oct 20, 2011. Objectives. . To understand how the immune system performs its major physiologic function.. Year 10 Science Life - psychology. A behaviour is . any observable action. made by a living . person. Examples . include; walking, crying, blinking, eating . etc.. All . of these activities can be . Kuby. . Immunology. , . 7e: Chapter 1. A historical perspective of immunology. What is immunity?. Immunity is the state of protection against foreign pathogens or substances (antigens). Latin term . What is it?. Innate Behavior. “Automatic” behavior. AKA instinct. Strong genetic component. Learned Behavior. What is it?. Learned Behavior. Behavior that is the result of experience or observation. Chapter 41 Key Concepts . 41.1 Animals Use Innate and Adaptive Mechanisms for Defense. 41.2 Innate Defenses Are Nonspecific. 41.3 Adaptive Defenses Are Specific. 41.4 The Humoral Adaptive Response Involves Antibodies. Maria Bleier . PATH 417. Overview. The Case. 10 . yr. old male patient . Ronnie McDonald.. Developed abdominal cramps, bloody diarrhea and low grade fever. Physician’s examination: . Asks about history in terms of food consumed – undercooked hamburgers from previous weekend as prime suspect. Immune Response. Adaptive Immune. 2. Adaptive or Acquired Immune Response. Protects against infectious agents and abnormal body cells . Amplifies the inflammatory . response. Activates complement. 3. Dr. . M.A.Thomas. . FUNCTIONS . OF THE IMMUNE SYSTEM. :. Recognize. , destroy and clear a diversity of pathogens. .. Initiate . tissue and wound healing processes. .. Recognize . and clear damaged self components. Immunostimulatory. and . fusogenic. liposomes (IFLs). . IFL may attract innate cells like DCs, macrophages leading to their . immunostimulation. and release of . proinflammatory. cytokines (pathway a). IFL may get . 19 April 2013. Professor . Julian Dyson. Section of Molecular Immunology. Department of . Medicine. Immune response to microbial challenge. Commensal microbiota. Links between innate and adaptive immunity.