PPT-Chapter 44 Drugs Acting on the Renin-Angiotensin-Aldosterone System

Drugs Acting on the ReninAngiotensinAldosterone System Physiology of the reninangiotensinaldosterone system Angiotensinconverting enzyme inhibitors Angiotensin II receptor blockers Aldosterone antagonists. INTRODUCTION as anticoagulant. The genomic DNA was ex- ID polymorphism was determined by al-(Tiret et al. 1992). ID were 5'-CTGGAGAGCCACTCCCATCCTTTCT-3' (Forward) and5'-GACGTGGCCATCACATTCGTCAGAT-3' (R hyperaldosteronism. (Conn’s syndrome):. An underdiagnosed disorder. i. n both humans and cats. . Michiel . Kerstens. . and. Hans Kooistra. Medulla. Zona Glomerulosa. Zona fasiculata. Zona Reticularis. Why is it important. Major intracellular ion (98%). Major determinant of resting membrane potential. (arrhythmia’s . etc. ). Long term = kidneys. Short term = intra-extra movement (serum K+ . doesn. Shannon Harris, DNP, FNP. Objectives. Causes of hypertension. Classifications of hypertension. Risk factors. Diagnosis . Complications. Management . Final thoughts. Hypertension. The #1 modifiable risk factor for stroke. Kelsey Davis, Courtney Getchell, Robert . Kolar. Introduction. We will be covering the topic of . prodrugs. , specifically a hypertension medication . Olmesartan. .. An introduction to . prodrugs. and what they are used for.. . ghazal. Each Adrenal gland lie superior to each kidney . . Pyramidal in shape .. 3- 5 cm in height , 3 cm in width , less than 1 cm thick. Mass 3.5 - 5 g . Gland differentiate in two distinct regions . ACEIs are among the most widely prescribed antihypertensive drugs. .. In general, these . drugs are . well absorbed from the GI tract, reaching peak . serum conc. within . 1 to 4 hours. . These drugs are . System. The Cardiovascular Continuum . Myocardial Infarction. Heart Failure. End-Stage Heart Disease. Plaque Rupture. Risk Factors. Hypertension. Hyperlipidemia. Diabetes. Atherosclerosis. Endothelial Dysfunction. Ali Al Khader, M.D.. Faculty of Medicine. Al-Balqa’ Applied University. Email: ali.alkhader@bau.edu.jo. Lecture outline. Adrenocortical hyperfunction (Hyperadrenalism):. -Hypercortisolism (Cushing syndrome). Hyperaldosteronism and Hypertension Hamid R. Hajmomenian, M.D. and Ramin Tabibiazar, M.D. 1 Case Report: A 65-year-old man was referred for evaluation of hypertension and hypokalemia, with potassiu , MD. Professor of Internal Medicine . UT Southwestern Medical Center. Dallas, Texas. Robert Toto. , MD. Associate Dean. Clinical and Translational Research . Director, Center for Translational Medicine . Prepared by . Dr . zainab. . eltrafi. Clinical pharmacist. Sympathomimetic amines that contain the 3,4-dihydroxybenzene group (such as epinephrine, norepinephrine, isoproterenol, and dopamine). are called catecholamines. . system. Dr Nish . Arulkumaran. SpR. and Clinical Research fellow. Imperial College London. GEP – Renal, . Feb2012. Systolic and Diastolic pressure. Heart cycle = systole and diastole. Systole = ventricular contraction = ejection . also known as . Conn Syndrome). A/Prof Jun Yang, MBBS FRACP PhD. Consultant Endocrinologist, Monash Health. Head, Endocrine Hypertension Group, Hudson Institute of Medical Research. Senior Research Fellow, Department of Medicine, Monash University.