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ESSENTIAL CONCEPTS IN THE USE OF SOMATOSTATIN ANALOGUES IN PATIENTS WITH NEUROENDOCRINE ESSENTIAL CONCEPTS IN THE USE OF SOMATOSTATIN ANALOGUES IN PATIENTS WITH NEUROENDOCRINE

ESSENTIAL CONCEPTS IN THE USE OF SOMATOSTATIN ANALOGUES IN PATIENTS WITH NEUROENDOCRINE - PowerPoint Presentation

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Uploaded On 2018-09-23

ESSENTIAL CONCEPTS IN THE USE OF SOMATOSTATIN ANALOGUES IN PATIENTS WITH NEUROENDOCRINE - PPT Presentation

Program Goals Program Outline History of Carcinoid Tumors Features of NETs Incidence of NETs Over Time by Primary Site Are NETs Really That Rare Patient Characteristics That Affect Treatment Selection ID: 677176

nets cont control references cont nets references control treatment ssas abbreviations tumor receptor clarinet therapy radionuclide characteristics peptide controlling

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Presentation Transcript

Slide1

ESSENTIAL CONCEPTS IN THE USE OF SOMATOSTATIN ANALOGUES IN PATIENTS WITH NEUROENDOCRINE TUMORSSlide2

Program GoalsSlide3

Program OutlineSlide4

History of Carcinoid TumorsSlide5

Features of NETsSlide6
Slide7

Incidence of NETs Over Time by Primary SiteSlide8

Are NETs Really That "Rare"?Slide9

Patient Characteristics That Affect Treatment SelectionSlide10
Slide11
Slide12

Pathology (Ki-67)Slide13

Other Classification and Nomenclature SystemsSlide14
Slide15
Slide16

Treatment Characteristics that Affect Treatment Selection (cont)Slide17

SSAs May Play Various Roles in the NET Treatment AlgorithmSlide18

SSAs Are Mainstay of Treatment for Controlling HormonesSlide19

SSAs Also Have a Role in Controlling Tumor GrowthSlide20

Physiology of Somatostatin and SSAsSlide21

Tools Used for Hormone ControlSlide22

ELECT Trial: Randomized Trial of Lanreotide for Carcinoid SyndromeSlide23

General Principles of SSA Dosing For Hormone ControlSlide24

Tools for Tumor Control in NETsSlide25

PROMID: Octreotide LAR for Tumor Control in Metastatic Midgut NETs Slide26

CLARINET: Antitumor Effects of Lanreotide in Metastatic NETsSlide27

Key Features of PROMID vs CLARINETSlide28

Principles of SSA Dosing For Tumor ControlSlide29

COOPERATE-2: Everolimus ± Pasireotide in Advanced Pancreatic NETsSlide30

Peptide Receptor Radionuclide TherapySlide31

NETTER-1: Peptide Receptor Radionuclide TherapySlide32

ConclusionsSlide33

AbbreviationsSlide34

Abbreviations (cont)Slide35

Abbreviations (cont)Slide36

Abbreviations (cont)Slide37

ReferencesSlide38

References (cont)Slide39

References (cont)Slide40

References (cont)Slide41

References (cont)Slide42

References (cont)Slide43

References (cont)