PPT-Managing Breast Cancer in the Genomic Era

Leisha A Emens MD PhD Associate Professor of Oncology Tumor Immunology and Breast Cancer Research Programs Johns Hopkins University Conflict of Interest Statement Biosante. Fikret Isik. Associate . Professor. September 16, 2013. Genomic BLUP - UofCopenhagen. 1. Cooperative Tree Improvement Program. North Carolina State University, Raleigh, . USA. Outline. Background. Realized genomic relationships. DR. A. AKHATOR FWACS, FICS. SENIOR LECTURER DELSU . CONSULTANT SURGEON DELSUTH. PRE-TEST. Breast cancer is the most common cancer in women in Nigeria . Breast cancer is the most common cause of cancer related deaths. SWAG Site Specific Group. Maxine Taylor. Senior Research Delivery Manager - Cancer. Friday 1. st. July . 2016. Clinical Research Network. West of England. South West Research Networks & SWAG. West of England. The Obstetrics & Gynecological Society of Bhopal. &. AMPOGS . Research Public Welfare Society. Screening tools. Clinical Breast examination. Breast self examination. Mammography. Ultrasonography/. Kristin . DePrince. Mattie, M.S.. Licensed / Certified Genetic Counselor. William G. Rohrer Cancer Genetics Program. Objectives. Describe . current approaches to genetic testing for hereditary cancer syndromes. Susan M. Domchek, MD. Basser Professor of Oncology. University of Pennsylvania . Sex. Age. Family . history. Depends on specific of family history. Depends on whether there is a k. nown . genetic . susceptibility. Dr. Ruth . Heisey. Family Physician/GP Oncologist. Women’s College Hospital/Princess Margaret . Cancer Centre. Clinician Investigator/Associate Professor. University of Toronto. Sandy Fawcett . RN(EC) NP-Adult. Inspection. Size. S. ymmetry (some variation is normal) . Shape. Contour (flattening, masses, and dimpling). S. kin (color, edema, rashes, thickening, and venous pattern). S. cars (previous surgery, injuries). BRCA2 is a tumor suppressor gene responsible for DNA repair . BRCA2 was discovered in breast cancer tumors of patients without BRCA1 mutations. Mice knockouts discovered that BRCA2 is directly involved in double strand break repair. Steven J. Katz MD MPH. Professor of Medicine and Health Management and Policy. University of Michigan . Allison Kurian MD M Sc.. Professor of Medicine and Medical Genetics . Stanford University . Guidelines 2019. group. of diseases. . All forms of cancer cause cells in the body to change and grow out of control. . Most types of cancer cells form a lump or mass called a . tumor. . . The tumor can invade and destroy healthy tissue. Cells from the tumor can break away and travel to other parts of the body. There they can continue to grow. . Most of these lesions are benign. Breast cancer is 2. nd. most common cause of cancer deaths in women, following. carcinoma of the lung. . The clinical significance of the . benign. conditions:. 1- possible clinical confusion with malignancy. Confluenceinternationalresearchproject-a consortiumconsortiathataimsto build a largecollaborativeplatformforgermlinegeneticstudiesbreastcancer GoalsConduct a large, multi Breast Cancer Cases Controls VOLUME 2


  
  Anuj Kumar and Michael Snyder FUNCTIONAL GENOMICSThe development andsystematic application ofexperimental methodologies toanalyse gene function on agenome-wide