PPT-CELL INJURY NECROSIS Dr.V.Shanthi

Associate Professor Department of Pathology Sri Venkateswara Institute of medical sciences Tirupathi CELL INJURY Cellular responses to stress amp injurious stimuli Normal cell homeostasis. An analgesic is any medicine intended to relieve pain. .. . Over-the-counter analgesics—that is, painkillers available without a prescription—include aspirin, acetaminophen, ibuprofen, naproxen sodium, and others. . 1 Liver – Necrosis 2 Liver – Necrosis Figure 1 Necrosis – sharply demarcated centrilobular necrosis in a male B6C3F1 mouse from a subchronic study. Figure 2 Necrosis – J. Matthew Velkey. matt.velkey@duke.edu. 454A Davison, Duke South (green zone). Cellular Adaptation to Injury or Stress. Injury or Stress. Increased demand. Decreased stimulation or lack of nutrients. infarction,Ischemic. bone necrosis). Femoral head blood supply.  . Humerus. head blood supply .  . X-Ray of hip joint. traction type. Ostiochonderitis. . dessicans. Crushing type. Assist.Prof.Dr. . . Baydaa. . H.Abdullah. Reversible . cell injury . . It . is called also . degeneration . .It is accumulation of normal substances (glycogen ,water) or abnormal (. Amyloid. ) inside the cell due to injury agent. classified into two main groups . Etab. A. AL-. Mosawe. Cell death. Cell . death falls into two main categories: . Apoptosis . and . necrotic cell death.  . Types of Cellular Necrosis. Liquefaction necrosis Digestive enzymes released by necrotic cells soften and liquefy dead tissue. Occurs in tissues, such as the brain, that are rich in hydrolytic enzymes.. A108 of Femoral Head Banuprakash S 1 1 Associate Professor, Department of Radio-Diagnosis, Sri Siddhartha Medical College, Agalakote, B H Road, Tumkur- 572107, India Corresponding author: Dr Banupra Associate Professor, Pathology. Sri Venkateswara Institute of Medical Sciences. Tirupathi. MALE GENITAL TRACT- PENIS. Congenital anomalies . Hypospadias. Epispadias. Phimosis. Inflammation. Tumors . Associate Professor, Pathology. Sri Venkateswara Institute of Medical Sciences. Tirupathi. TESTIS AND EPIDIDYMIS. CONGENITAL ANOMALIES. Anomalies include. . Cryptorchidism. Aplasia . Fusion (. synorchism. Professor and HOD. Department of Pathology. OVERVEIW. DEFINITION OF ATHEROSCLEROSIS. RISK FACTORS. HYPOTHESIS REGARDING PATHOGENESIS. COMPLICATIONS. CLINICAL MANIFESTATIONS. ATHEROSCLEROSIS. Atherosclerosis means . Sri . Venkateswara. Institute of Medical Sciences. Tirupathi. . . ALL AND CLL/SLL. . ACUTE LYMPHOBLASTIC LEUKEMIA. Primarily a disease. . of children. Age -. Majority occur between 1-5 . yrs. ( second peak in adults between 30-40 . ,. Associate Professor, Pathology. Sri Venkateswara Institute of Medical Sciences. Trupathi. ISCHEMIC HEART DISEASE (IHD). IHD represents a group of . pathophysiologically. related syndromes resulting from myocardial ischemia – an . . Cellular. . Responses. . to. Stress and . Noxious. . Stimuli. Sequence. . of. . reversible. . cell. . injury. and . cell. . death. . . Necrosis. and . apoptosis. are the . two. major . DILI. Prepared by:. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). . introduction :. Drug toxicity should always be considered in the differential diagnosis of patients presenting with acute liver failure, jaundice or abnormal liver biochemistry..