PPT-Drugs induced liver injury

DILI Prepared by Dr Muntadher Abdulkareem Abdullah MBChBCABMFIBMSFIBMSGEampHEP introduction Drug toxicity should always be considered in the differential diagnosis of patients presenting with acute liver failure jaundice or abnormal liver biochemistry. JUNIOR RESIDENT. T.B.HOSPITAL. ANTITUBERCULOSIS TREATMENT INDUCED HEPATOTOXICITY. Tuberculosis is a disease caused by Mycobacterium tuberculosis, a bacteria that is passed between people through the air. . prevention of drug-induced . liver injury. Drug-induced liver injury (DILI) is increasingly . being . recognised. . as . a significant cause . of both acute . and chronic . liver disease. .. The most commonly . Soheil Altafi MD. 1/27/15. DILI- Table of Contents. Introduction. Epidemiology. Liver - Drug Metabolism. Factors influencing Drug Metabolism. Mechanisms of Drug-induced Hepatotoxicity. Clinical Presentation. Soheil Altafi MD. 1/27/15. DILI- Table of Contents. Introduction. Epidemiology. Liver - Drug Metabolism. Factors influencing Drug Metabolism. Mechanisms of Drug-induced Hepatotoxicity. Clinical Presentation. Yolande Lucire and Christopher Crotty . . Why do some people believe that they do?*. What is the link between illicit street drug use and being diagnosed with “treatment-refractory schizophrenia”?. Navy . ACP 2014. Medication . DILI-. emma. : . The Masquerade . of Drug . Induced Liver . Injury. The views expressed in this presentation are those of the author and do not necessarily reflect the official policy or position of the Department of the Navy, Army, Department of Defense, nor the U.S. Government. . Department of Internal Medicine II, Division of Gastroenterology and Hepatology, Klinikum Hanau, Hanau, Academic Teaching Hospital of the Medical Faculty, Goethe University Frankfurt/ Main, Frankfurt/ 2017; 16 (3): 442-450 Abdominal ultra-tients were followed up for at least 6 months or until Patients with pre-exist- MELD score was calculated (creatinine mg/dL) + 3.8 x log (international normal- 2017 16 2 308-311Table 1A aspartate aminotransferase AST increased 80 U/L Zinc sulfate turbidity 4 U total was positive for ipraglifloz-DISCUSSION However we havecytomegalovirus and Epstein-Barr viru Department of Internal Medicine II Division of Gastroenterology and Hepatology Klinikum Hanau Hanau Academic Teaching Hospital of the Medical Faculty Goethe University Frankfurt/ Main Frankfurt/Main G 2017 16 2 308-311Table 1A aspartate aminotransferase AST increased 80 U/L Zinc sulfate turbidity 4 U total was positive for ipraglifloz-DISCUSSION However we havecytomegalovirus and Epstein-Barr viru 4. th. stage . Assistant lecturer: Shahad . S.aldeen. . Department of pharmacology and toxicology . May-2021. Headline. Introduction . Types of liver injury . Steatosis. Necrosis. Apoptsis. . Fibrosis . ANTI & HEPATOTOXICITY : Antimicrobials include antibacterial, antiviral, antifungal, antiparasitic drugs commonly used against microbiome in routine pediatric practice. Most of the drugs are metaboli DILI. Prepared by:. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). Objectives :. At the end of this lecture, the student should know:. What is DILI?. What are the different pattern of DILI?.