PPT-Drug-Induced Liver Injury

Soheil Altafi MD 12715 DILI Table of Contents Introduction Epidemiology Liver Drug Metabolism Factors influencing Drug Metabolism Mechanisms of Druginduced Hepatotoxicity Clinical Presentation. JUNIOR RESIDENT. T.B.HOSPITAL. ANTITUBERCULOSIS TREATMENT INDUCED HEPATOTOXICITY. Tuberculosis is a disease caused by Mycobacterium tuberculosis, a bacteria that is passed between people through the air. . prevention of drug-induced . liver injury. Drug-induced liver injury (DILI) is increasingly . being . recognised. . as . a significant cause . of both acute . and chronic . liver disease. .. The most commonly . Soheil Altafi MD. 1/27/15. DILI- Table of Contents. Introduction. Epidemiology. Liver - Drug Metabolism. Factors influencing Drug Metabolism. Mechanisms of Drug-induced Hepatotoxicity. Clinical Presentation. Navy . ACP 2014. Medication . DILI-. emma. : . The Masquerade . of Drug . Induced Liver . Injury. The views expressed in this presentation are those of the author and do not necessarily reflect the official policy or position of the Department of the Navy, Army, Department of Defense, nor the U.S. Government. . Department of Internal Medicine II, Division of Gastroenterology and Hepatology, Klinikum Hanau, Hanau, Academic Teaching Hospital of the Medical Faculty, Goethe University Frankfurt/ Main, Frankfurt/ 2017; 16 (3): 442-450 Abdominal ultra-tients were followed up for at least 6 months or until Patients with pre-exist- MELD score was calculated (creatinine mg/dL) + 3.8 x log (international normal- 2017 16 2 308-311Table 1A aspartate aminotransferase AST increased 80 U/L Zinc sulfate turbidity 4 U total was positive for ipraglifloz-DISCUSSION However we havecytomegalovirus and Epstein-Barr viru Department of Internal Medicine II Division of Gastroenterology and Hepatology Klinikum Hanau Hanau Academic Teaching Hospital of the Medical Faculty Goethe University Frankfurt/ Main Frankfurt/Main G Key words Acute hepatitis toxic hepatitis slimming tea Tabak F Akut Hepatitler CerrahpaFakltesi Srekli Titimi Etkinlikleri Hepato-Bilier Sistem ve Pankreas HastalklarSempozyum Dizisi 2002 2843-55 Sh 2017 16 2 308-311Table 1A aspartate aminotransferase AST increased 80 U/L Zinc sulfate turbidity 4 U total was positive for ipraglifloz-DISCUSSION However we havecytomegalovirus and Epstein-Barr viru 23 European Review for Medical and Pharmacological Sciences2017; 21 (1 Suppl): 23-36 F.R. PONZIANI1, S. BHOORI2, M. POMPILI1, M.A. ZOCCO1, M. BIOLATO1, G. MARRONE1, A. GASBARRINI1, V. MAZZAFERRO2, A. ANTI & HEPATOTOXICITY : Antimicrobials include antibacterial, antiviral, antifungal, antiparasitic drugs commonly used against microbiome in routine pediatric practice. Most of the drugs are metaboli DILI. Prepared by:. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). . introduction :. Drug toxicity should always be considered in the differential diagnosis of patients presenting with acute liver failure, jaundice or abnormal liver biochemistry.. DILI. Prepared by:. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). Objectives :. At the end of this lecture, the student should know:. What is DILI?. What are the different pattern of DILI?.