PPT-Drug-Induced Liver Injury

Soheil Altafi MD 12715 DILI Table of Contents Introduction Epidemiology Liver Drug Metabolism Factors influencing Drug Metabolism Mechanisms of Druginduced Hepatotoxicity Clinical Presentation. By Aidan Cross and Tom Grant. How many phases of drug . metabolism are there? (1 mark). 3 Phases. . What . is phase 1 of drug metabolism? (2). Provide a functional group (e.g. OH or NH. 2. ) to:. increase polarity of the drug. prevention of drug-induced . liver injury. Drug-induced liver injury (DILI) is increasingly . being . recognised. . as . a significant cause . of both acute . and chronic . liver disease. .. The most commonly . . Jessica Colyer, MD . 2 March 2018. D. isclosures. I am an employee of UK. I have no relevant financial relationships. Objectives. Summarize the types of . sequelae that . can occur following an opiate- induced brain injury. Introduction. Epidemiology . Drug-induced Aplastic anemia. Drug-induced Hemolytic anemia. Drug-induced Neutropenia and Agranulocytosis. Drug-induced Thrombocytopenia. Drug-induced Megaloblastic anemia. Liver dysfunction and Drugs metabolism Dr V.Sebghatollahi Isfahan university of medical science Liver Functions: Metabolism – Carbohydrate, Fat & Protein Secretory – Bile acids, bile salts disease. Penny North-Lewis. Paediatric Liver Pharmacist. Leeds . Children’s Hospital. September 2019. Where is the liver?. What does the liver do?. Synthesis. . (e.g. albumin & clotting . factors, cholesterol). 2017; 16 (3): 442-450 Abdominal ultra-tients were followed up for at least 6 months or until Patients with pre-exist- MELD score was calculated (creatinine mg/dL) + 3.8 x log (international normal- 2017 16 2 308-311Table 1A aspartate aminotransferase AST increased 80 U/L Zinc sulfate turbidity 4 U total was positive for ipraglifloz-DISCUSSION However we havecytomegalovirus and Epstein-Barr viru Department of Internal Medicine II Division of Gastroenterology and Hepatology Klinikum Hanau Hanau Academic Teaching Hospital of the Medical Faculty Goethe University Frankfurt/ Main Frankfurt/Main G 2017 16 2 308-311Table 1A aspartate aminotransferase AST increased 80 U/L Zinc sulfate turbidity 4 U total was positive for ipraglifloz-DISCUSSION However we havecytomegalovirus and Epstein-Barr viru ANTI & HEPATOTOXICITY : Antimicrobials include antibacterial, antiviral, antifungal, antiparasitic drugs commonly used against microbiome in routine pediatric practice. Most of the drugs are metaboli DILI. Prepared by:. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). . introduction :. Drug toxicity should always be considered in the differential diagnosis of patients presenting with acute liver failure, jaundice or abnormal liver biochemistry.. Download PDF Fatty Liver Remedy™ eBook by Layla Jeffrey - a comprehensive guide designed to address and alleviate the symptoms of fatty liver disease through natural and lifestyle-based approaches. Géraldine. Celliere. MAMBA team. Modeling . and Analysis for Medical and Biological . Applications. Led by Marie . Doumic. -Jauffret. Joint with UPMC. At Inria, focuses on:. mathematical modeling of biological tissues (liver, tumors).