PDF-309SGLT2 inhibitor and liver injury

2017 16 2 308311Table 1A aspartate aminotransferase AST increased 80 UL Zinc sulfate turbidity 4 U total was positive for ipragliflozDISCUSSION However we havecytomegalovirus and EpsteinBarr viru. Function. Dr. . Baghbanian. M.. Gastroenterologist. Shaheed. . Sadoughi. hospital / 2012. . liver tests. (. 1) detect the presence of liver . disease. . (2) . distinguish . different types of liver . Soheil Altafi MD. 1/27/15. DILI- Table of Contents. Introduction. Epidemiology. Liver - Drug Metabolism. Factors influencing Drug Metabolism. Mechanisms of Drug-induced Hepatotoxicity. Clinical Presentation. It permits examination of liver cells. . Liver biopsy is especially useful when clinical findings and laboratory tests are not diagnostic.. Bleeding and bile peritonitis after liver biopsy are the major complications;. Unite one. Second Lab. .. The two lung abscesses seen here are examples of . liquefactive necrosis. in which there is a liquid center in an area of tissue injury. One abscess appears in the . upper lobe . Due to liver damage and healing. Progresses through 4 stages, ending in cirrhosis. Liver cirrhosis causes more than . 1 million deaths per year. http://depts.washington.edu/hepstudy/definitions/uploads/49/Liver_Cirrhosis.png. Causes:. - infectious Hepatitis. : viral, Bacterial, Parasitic, and Helminthic. Autoimmune Hepatitis. Drug- and Toxin (Alcohol). Metabolic. infectious Hepatitis. Several clinical syndromes may develop following exposure to hepatitis viruses: . ). The liver is vulnerable to a wide variety of metabolic, toxic, microbial, circulatory, and neoplastic insults. . The major primary diseases of the liver are viral hepatitis, nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease, and hepatocellular carcinoma (HCC).. By. Zohreh. . Rahimi. Professor of Clinical Biochemistry. 1. TESTS OF LIVER INJURY. PLASMA ENZYME LEVELS. As metabolically complex cells, hepatocytes contain high levels of a number . of . enzymes. With liver injury, these enzymes may leak into plasma and can . Liver is the largest organ of the body.. Sets in the right side of the belly.. Weighs between 1.0-2.5 kg.. Heavier in males than females.. It is reddish in color & feel rubbery to touch.. Have two sections-right & left lobe.. . . 1. .Metabolic Functions. :. U. rea cycle. Glycogen synthesis. Vitamin Metabolism. Minral Metabolism. Lipid Metabolism. Glycolysis. . . 2. .Excretory Functions. :. Cholesterol. Bile Pigments. A. . Ansari. Deptt. . Of Pathology. JNMC,AMU. Fatty liver. Gross Description. Fatty liver is caused by the excessive deposition of fats, especially triglycerides, in the cells of the liver.. The liver appears enlarged and pale/yellowish in . Patterns of liver injury . Ballooning degeneration . Pattern of hepatic injury -. steatosis. Microvesicular. . steatosis. . Macrovesicular. . steatosis. . Patterns of hepatic injury-Apoptosis . Councilman body . BY . Dr.Qutaiba. . Abdulkareem. . Qasim. . PhD. . In Clinical . Biochemistry. FUNCTIONS OF THE LIVER. General metabolic functions :. 1-. . Glycogenesis. and . glycogenolysis. 2-. . Gluconeogenesis. Download PDF The Fatty Liver Solution™ eBook by Duncan Capicchiano - A natural and effective approach to tackling fatty liver disease.