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753obituaryZena Werb as a graduate student at Rockefeller University circa 1971 Credit Rockefeller Grad News and Notes June 1971 Vol 2 No 10NATURE CA VOL 1 ST 2020 753754 wwwnaturecomnatcancer75. By: . Weigang. . wang. , . sumanta. . goswami. , Erik . sahai. , . jeffrey. . b. . wyckoff. , Jeffrey E. . Segall. and John S. . Condeelis. Presented By: Lana . Awad. and Sebastian Lukjan. Motivation of research, why they did what they did…. c. aught in the act of invading: Their strategy for enhanced cell motility” . By Xinqi Li and Megan Roytman. Weigang . Wang, . Sumanta . Goswami, . Erik . Sahai, . Jeffrey B. . Wyckoff, . Jeffrey E. . By: . Weigang. . wang. , . sumanta. . goswami. , Erik . sahai. , . jeffrey. . b. . wyckoff. , Jeffrey E. . Segall. and John S. . Condeelis. Presented By: Lana . Awad. and Sebastian Lukjan. Motivation of research, why they did what they did…. Proposed an efficient exosome-based tumor antigens-adjuvant co-delivery system:. Genetically engineered tumor cell-derived exosomes: . Endogenous tumor antigens. Immunostimulatory. . CpG. DNA. Source cells (for exosome): murine melanoma B16BL6. And. Dynamical . . Modeling Of Tumor Decay. Amy W. Daali. Ph.D. . . Defense. Spring 2015. Electrical . and Computer Engineering Department . University of Texas at San Antonio.  . PCA based Algorithm for Longitudinal Brain Tumor Stage Classification & Dynamical Modeling of Tumor Decay . At diagnosis 80% of patients will present with metastasis.. Only 20% of these cases are clinically detectable.. Current imaging modalities are expensive and only detect established secondary tumors.. Do Now. Why did Steve Jobs’ tumor metastasize to his liver and lung but not other organs?. Is it primary or secondary?. Primary tumor of lymph node (lymphoma). Secondary tumor (melanoma) in lymph node. LEC.4. Examples of tumor suppressor genes:. 1. RB gene:. This is the . first discovered suppressor gene. , . loss of normal RB gene was discovered initially in Retinoblastoma, but recently proved it lost in many tumors (breast cancer, bladder & lung cancer, osteosarcoma).. Normal parathyroid. Incidental cyst. (not important). capsule. The neoplasm. Normal parathyroid. Parathyroid adenoma. Tumor behavior is . much more important . than morphology. Tumor invasion in the capsule. Séminaire. des . doctorants. William . Weens. BANG, . Inria. November. . 15th . 2011. Outline. Cancer. Systems Biology. Mathematical description. Application to liver tumor. Conclusion. Definition. Glioblastoma. Maria Gubbiotti, MD/PhD Candidate. Jefferson Medical College. The burden of brain cancer. <1% chance of developing malignant brain cancer during one’s lifetime. In 2019:. ~23,820 malignant tumors of the brain and spinal cord will be diagnosed. Neoplasia. is a process of “new growth” in which normal cells undergo irreversible genetic changes, which render them unresponsive to ordinary controls on growth exerted from within the “transformed” cell or by surrounding “normal” cells.. . has 5 units. Each unit lasts about a week and covers one of the critical questions we will need to answer if we want to understand cancer.. Unit 1. : What is cancer and why should we care?. Unit 2. Intervista a Federico . Cappuzzo. Background:. Programmed death-ligand 1 (PD-L1) expression on tumor cells (TC) or tumor-infiltrating immune cells (IC) is associated with OS, PFS and ORR in pts with advanced NSCLC treated with atezolizumab (anti-PDL1, MPDL3280A; Spigel et al, Spira et al, ASCO 2015), indicating that PD-L1 expression on both TC and IC is important for anti-tumor immunity. However, these 2 distinct expression patterns suggest the existence of previously unidentified NSCLC subtypes with distinct immunologic profiles. .