PPT-Isolation of rare circulating tumor cells in cancer patient

Nagrath amp Sequist et al 2007 Journal Presentation Brigitte Morales amp Leanna Morinishi December 8 th 2011 Nagrath S Sequist L et al Nature 4507173 20071235239 Print. 1111joim12047 Circulating tumour cells insights into tumour heterogeneity D F Hayes C Paoletti From the Breast Oncology Program University of Michigan Comprehensive Cancer Center Ann Arbor MI USA Abstract Hayes DF Paoletti C University of Michigan C CampaignTracker. A brief overview of its design and function and what we have learned so far.. Background & Purpose. The . CampaignTracker. is a tool built to house Rare’s reporting tools and processes that provide a consistent global language with which to measure and assess the progress and quality of Rare’s work around the world.. A Disease of Mitosis. 1. Cancer: a Disease of Mitosis. Cancer is a . disease of . mitosis – resulting in uncontrollable mitotic division.. Cells do not live forever, and they will reach a point where they will . Circulating Tumor Cells (CTC). Metastasis. : the spread of cancer from its primary site to other places in the body..  Metastatic disease is the most common cause of cancer-related death in patients with solid tumors.. Gaorav. P. Gupta and Joan . Massague. Gabriella F. de Paz and Susana S. . Hak. Fall 2011, 20.309. An Evolutionary Metaphor. Evolution = environmental stresses select for organisms with advantageous survival traits. Arshed A. Quyyumi, MD . Professor of Medicine . Emory Clinical Cardiovascular Research Institute (ECCRI). Emory University School of Medicine. Atlanta, GA. Grant support: . National Institutes of Health, . Recurrence and Metastasis: A Major Factor in Cancer-related Deaths. Cancer is the second leading cause of death in the United States. 1. Despite advances in cancer treatment, many patients develop:. Lucio Miele, M.D., Ph.D.. The Basics of Cancer Biology. With special thanks to. Andrew Hollenbach, PhD. Wanguo Liu, PhD. Antonio Pannuti, PhD. For providing original materials. Course outline. The Selfish Cell: Darwin and Cancer. By: . Weigang. . wang. , . sumanta. . goswami. , Erik . sahai. , . jeffrey. . b. . wyckoff. , Jeffrey E. . Segall. and John S. . Condeelis. Presented By: Lana . Awad. and Sebastian Lukjan. Motivation of research, why they did what they did…. At diagnosis 80% of patients will present with metastasis.. Only 20% of these cases are clinically detectable.. Current imaging modalities are expensive and only detect established secondary tumors.. Youn Wha Kim Sung Wan Kim Yong-Koo Park Chondromyxoid fibroma (CMF) is a relatively rare bone tumorthat was first described by Jaffe and Lichtensteinin 1948. Thistumor makes up less than 1% of all bon Charis Girvalaki. ECPC Director. European Cancer Patient Coalition. . Every year, more than . 3 million. . people are diagnosed with cancer. An estimated . . 3.9 million . people were faced with a diagnosis of cancer and . The market for circulating tumour cells is primarily driven by the rising understanding of
their diagnostic and clinical utility, which has prompted an increase in circulating tumour cell research in
an effort to develop efficient diagnostic tools. Intervista a Federico . Cappuzzo. Background:. Programmed death-ligand 1 (PD-L1) expression on tumor cells (TC) or tumor-infiltrating immune cells (IC) is associated with OS, PFS and ORR in pts with advanced NSCLC treated with atezolizumab (anti-PDL1, MPDL3280A; Spigel et al, Spira et al, ASCO 2015), indicating that PD-L1 expression on both TC and IC is important for anti-tumor immunity. However, these 2 distinct expression patterns suggest the existence of previously unidentified NSCLC subtypes with distinct immunologic profiles. .