In an average young adult male 18 of body weight is protein and related substances 7 is minerals 15 is fat 40 The remaining 60 is water total body water TBW 13 Extra cellular fluid ECF ID: 1037441
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1. BODY FLUID In an average young adult male:18% of body weight is protein and related substances.7% is minerals .15 % is fat40 %The remaining : 60 % is water ( total body water) (TBW)
2. 1/3 Extra cellular fluid (ECF)2/3 Intro cellularfluid (ICF)40% of body weight)( 20% of body weight) TBW 60% of body weight3/4 (15%) outside the blood vessels (interstitial fluid. )1/4 (5%) inside the blood vessels (PLASMA)
3. The composition of plasma is similar to that of (ECF). Except that plasma protein are more in plasma than in interstitial fluid. Transcellular fluid: Cerebrospinal fluid ,aqueous humor in the eyes. These are related to the (ESF),but separated from the(ESF),and relatively small in volumes.
4. Total body water content varies with body fat content, sex, and age. Because fat cells contains little water , where as lean tissues (skeletal muscles) is rich in water.Total body water lower in women than men , and in both sexes , the values tend to decrease with age.The (ESF) volume/ ( ICF) volume ratio is larger in infants and children than it is in adults. Therefore, dehydration develops more rapidly and frequently, more sever in children than adult.All body fluids have the same PH (7.4± 0.05) which is slightly less in the (ICF). Because of the metabolism inside the cells(7.2).All body fluids have the same osmolality (290mosm /L) but differs in their ions because of selective permeability of cell membrane.
5. (ECF) contains large quantities of Na+ but only small quantities of K+. Exactly the opposite is true in the( ICF)The (ECF) contains large quantities of chloride , while the (ICF) contains very little. The concentration of phosphates and proteins in (ICF) are considerably greater than In the (ECF).Plasma proteins (7.3g/dl), interstitial fluid protein (2g/di). pressure called plasma colloid osmotic pressure (plasma oncotic pressure)). (28mmHg) .This pressure prevent loss of water from the blood capillaries to the interstitial fluid. Plasma osmotic pressure (28mmHg)(19 mmHg) due to plasma protein (9mmHg due to sodium)
6. Routes ofgains and loss of water. a. Water gain: In healthy individuals fluids are gained by drinking & eating. In illnesses fluid may be gained by parentral route (i.e. I.V). Enteral route (i.e. nasogastric feeding).b. Water loss: Organs of'fluid loss includes: (Kidneys, lungs, skin and gastrointestinal tract).
7. Functions of body fluids: Body fluids are in constant motion maintaining healthy living conditions for body cells. Nutrients (glucose, A.A, Ions) and O2 transported by the (ECF) to the cells and waste products are carried a way from the cells therefore all the cells live in the same environment which is the (ECF).So it's called the (internal environment) of the body. So for cell .-living, growing and function it's important to maintain a static or constant internal environment(homeostasis
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