PPT-Lecture 5b Aldol Condensation

Introduction The acidity of organic compounds is often determined by neighboring groups because they can help stabilizing the resulting anion ie halogen nitro etc because of their . brPage 2br What is condensation Condensation is caused when water vapour comes into contact with cold surfaces and condenses to form dampness or water droplets Air can contain varying amounts of water vapour warm air can hold more water vapour than But reaction can be engineered to force aldol product Enolate can be formed transiently as above or uantitativel e w LDA an unsaturated ketone qy In base alone reaction stops at alcohol In base and heat aldol is dehydrated loses H O The Aldol Co Th is makes the aldol reaction an important reaction for organic synthesis Origina lly the al dol reaction used ethanal see below and the refore the product contained both an ald ehyde and an alcoh ol functional group thus it became known as the al Induced. Winds. a supplemental theorem to the traditional . thermal. wind model. Deborah E. Ross . University of Montana . Department of Physics and Astronomy. Overview. Basic Meteorological Assumptions. 18-4. Alkylation of enolates can be difficult to control.. The alkylation of an aldehyde or ketone enolate is an example of a nucleophilic substitution reaction.. The alkylation of aldehydes and ketones is complicated by several unwanted side reactions.. Malcolm Thornton. Managing Director, Proten Services. What is the PCA?. The Property Care Association (PCA) is the trade association representing members, promoting best practice and providing technical guidance in the following sectors:. Conditional Density Propagation for Visual Tracking. Michael . Isard. and Andrew Blake, IJCV 1998. Presented by . Wen. Li. Department of Computer Science & Engineering. Texas A&M University. 1. Chapter 19. Condensation and Conjugate Addition Reactions of Carbonyl . Compounds. More Chemistry of Enolates. Ch. . 19 . - . 2. About The Authors. . These PowerPoint Lecture Slides were created and prepared by Professor William Tam and his wife, Dr. Phillis Chang. . , •AJLn equLOLrLum etZeen Netone nd OdoO OLes •,n cLd Oone rectLon stops t OcoKoO.•,n cLd Claire O’Neill. Environmental Protection, Public Health and Housing. Environmental Health Service. Environmental Protection , Public Health and Housing. Food Safety. Health and Safety. Community Safety. Grace College. Chapter . 22. Lecture. Organic Chemistry. , . 9. th. Edition. L. G. Wade, Jr.. Condensations and Alpha Substitutions of Carbonyl Compounds. © 2017 Pearson Education, Inc.. Alpha Substitution. . 73. April. . 25, . 2011. . . -H Reactivity . (J&F Ch. 19). Condensations . (J&F Ch. 19). Fischer’s Glucose Proof - Introduction. . This. For copyright notice see final page of this file. Preparation of . Benzalacetophenon. (. Chalcones. ). 2. Are(. enone. ) or α, β unsaturated aromatic ketones containing the reactive keto ethylene group –CO– CH=CH-. Many of the chalcones are highly biological active which have medicinal and pharmaceutical applications. a. -carbon and . b. -carbon of Carbonyl Compounds. (Chapters . 18 & . 19). . Qualitative . Iodoform. Test . for methyl ketones. 1. In this chapter . :. Reactions that derive from the weak acidity of hydrogen atoms on carbon atoms adjacent to a carbonyl group. These hydrogen atoms are call the .