PPT-Alkylation of Aldehydes and Ketones

Author : alexa-scheidler | Published Date : 2015-11-26

184 Alkylation of enolates can be difficult to control The alkylation of an aldehyde or ketone enolate is an example of a nucleophilic substitution reaction The

Presentation Embed Code

Download Presentation

Download Presentation The PPT/PDF document "Alkylation of Aldehydes and Ketones" is the property of its rightful owner. Permission is granted to download and print the materials on this website for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.

Alkylation of Aldehydes and Ketones: Transcript


184 Alkylation of enolates can be difficult to control The alkylation of an aldehyde or ketone enolate is an example of a nucleophilic substitution reaction The alkylation of aldehydes and ketones is complicated by several unwanted side reactions. Studies on Direct and Indirect Reductive Amination Procedures Ahmed F AbdelMagid Kenneth G Carson Bruce D Harris Cynthia A Maryanoff and Rekha D Shah The R W Johnson Pharmaceutical Research Institute Department of Chemical Development Spring House P In General. Fragrant odors. Basic building block of housing materials. Hormones. Digestion. Vision. 2. In General. Carbonyl group. C=O. Aldehydes. RCH=O. Formyl. Ketones. RC=OR’. 3. Nomenclature. Learning Objectives:. Know the general formula for alcohols.. Be able to name alcohols.. Describe the shape of alcohols.. Classify primary, secondary, and tertiary alcohols.. Describe the physical properties of alcohols.. 15-11. Carbon-carbon bonds to benzene can be created using a sufficiently electrophilic carbon based electrophile.. To create the necessary electrophilic carbon atom, a Lewis acid such as AlCl. 3. is employed.. 17-1. The aldehyde function takes precedence over the ketone group in nomenclature.. Simpler aldehydes often retain their common names. These are constructed by dropping the –. ic. or –. oic. . ketons. Formaldehyde.. Acetaldehyde.. Chloral hydrate.. Benzaldehyde. .. Aceton. .. Acetophenone. .. It . contains variety of chemical compound including benzoate, . ceosol. ,, . benzaldehyde. , y-. terpineol. 17-7. Aldehydes and ketones form hemiacetals reversibly.. The reaction of alcohols with aldehydes and ketones parallels the reaction with water:. These equilibria usually favor the starting carbonyl compound.. 18-1. The pK. a. values of the . -hydrogens of aldehydes and ketones range from 16 to 21, comparable to those of alcohols (15-18).. Strong bases can remove  hydrogens leading to anions called . 17-4. Laboratory syntheses of aldehydes and ketones use four common methods.. Oxidation of alcohols:. Ozonolysis:. Hydration of the carbon-carbon triple bond y. ields enols that tautomerize to carbonyl compounds.. 1. Chapter 16. Aldehydes & Ketones:. Nucleophilic Addition. to the Carbonyl Group. Ch. 16 - . 2. About The Authors. . These PowerPoint Lecture Slides were created and prepared by Professor William Tam and his wife, Dr. Phillis Chang. . Lesson on the following:. The Carbonyl group. Nomenclature for . Aldehydes. and . Ketones. Properties of . Aldehydes. and . Ketones. . 1.5 . Aldehydes. . and . Ketones. Aldehydes and Ketones. Do Now: Write the molecular formula for the two sugars on the right. Are they isomers?. General formula: R. . C. . H or RCHO. Carbonyl group . just like ketone except . always. . at end of aldehyde . a. -carbon and . b. -carbon of Carbonyl Compounds. (Chapters . 18 & . 19). . Qualitative . Iodoform. Test . for methyl ketones. 1. In this chapter . :. Reactions that derive from the weak acidity of hydrogen atoms on carbon atoms adjacent to a carbonyl group. These hydrogen atoms are call the . Carbonyl Compounds. Contain the carbonyl group . C=O. . Aldehydes: . R may be hydrogen, usually a carbon containing group. Ketones: . R contains carbon. Short. forms. Structures of Aldehydes . and Ketones.

Download Document

Here is the link to download the presentation.
"Alkylation of Aldehydes and Ketones"The content belongs to its owner. You may download and print it for personal use, without modification, and keep all copyright notices. By downloading, you agree to these terms.

Related Documents