PPT-Sickle Cell Anemia

By Jarrett Devose Jordan Patten and Michael Lamb Sickle cell anemia is a disease passed down through your family it causes red blood cells to form in a odd crescent shape Red blood cells are usually shaped like a . EXAMINING PREVALENCE OF TOBACCO,. ALCOHOL, ILLICIT DRUG USE IN. ADULTS WITH SICKLE CELL ANEMIA. Catherine A. Seamon, Darlene T. Allen, . James G. Taylor VI, Jonathan Wilson, Gregory J. Kato . Disclosures. b. d. g. a. a. Chromosome 16. Chromosome 11. 25%. 25%. a. a. b. d. g. 25%. 25%. 48%. 48%. 1.5%. 0.5%. 1.5%. 0.5%. Hemoglobin synthesis. a. a. a. a. a. a. b. g. d. b. d. g. HbA. HbF. HbA. 2. 98%. ~1%. Jenny Pham. Protein Structure & Function. Spring 2015. Outline. Normal Adult Hemoglobin (. Hb. A). Function: Deoxygenated v. Oxygenated. Mutation in . Hb. A. Sickle Cell Hemoglobin (. Hb. S). Sickle Cell Anemia. By Jessica Sambo. Drepanocytes . Most common of sickle cell diseases. Autosomal recessive genetic disorder. Hemoglobin S. First in Africa. Discovered in US in 1910. “cells in the shape of sickles”. was developed to create a greater awareness in . the Nashville . community of Sickle Cell Disease and to raise . funds for . patient care, . social services. , and research. . All . proceeds from the event . Presenter: Bridget H. Wilson, Ph.D., MS, RN. Introduction. Sickle cell disease (SCD) pain continues to emerge among adolescents. Over 98,000 individuals are believed to have SCD within the United States. . Katie Coltharp and Mariela Saenz. Names of Disorder. HbS. disease. Hemoglobin S disease. Hemoglobin SS disease. Sickling. disorder due to hemoglobin S. Sickle cell disease (broad term). Sickle cell disorders (broad group of conditions). Gary Strokosch, MD. Jane Litvin, MS. Introduction. History of . sickle cell disease . (SCD). Present in Africa for at least . 5,000. . years. 1910-. . Discovered in US. Walter Clement Noel – dental student from Grenada studying in Chicago. . What is the most common genetic disorder in the United States?. Background . Inheritance. Pathophysiology. Diagnostic . testing. Prognosis. Management of acute illness. Long-term management. Treatment options. Ashley Jones-. Ragle. , MD. 12/10/2014. SICKLE CELL DISEASE. e.a. .. 24 year old . kurdish. female presents to . vumc. . ed. with severe back pain and left leg pain complicated by severe tachycardia (170s).. Dr. Soheila . zareifar. Department of pediatric hematology/oncology. Shiraz university of medical sciences. Qeshm. 2018. Transfusion in Sickle Cell. In sickle cell disease transfusions improve blood flow by reducing the proportion of red cells capable of forming sickle hemoglobin polymer. . Ali Al Khader, M.D.. Faculty of Medicine. Al-Balqa’ Applied University. Email: ali.alkhader@bau.edu.jo. Sickle Cell Anemia. The . most common familial hemolytic . anemia in . the . world. Sickle . cell . globin. chains. Abnormalities in these proteins are referred to as . hemoglobinopathies. Two hemoglobin gene clusters are involved in the production of hemoglobin and are located at the end of the short arm of chromosomes 16 and 11, respectively. . Ass. Prof. . Abeer. . Anwer. Ahmed. Sickle cell . anaemia. Ass. Prof. . Abeer. . Anwer. Ahmed. Sickle cell disease is a group of . haemoglobin. disorders . resulting from . the inheritance of the sickle β‐.