PPT-Macrocytic anemia UNIVERSITY OF BASRA

COLLEGE OF MEDICINE DEPARTMENT OF PATHOLOGY AND FORENSIC Medicine Dr Alaa ARazak Abood Iraqi Board of Haematopathology O bjectives Define macrocytic anemia and mention the major causes. Mike Clark, M.D.. Anemia. is a decrease in the normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency.. Greg . Radin. 7/9/2013. Anemia. Definition:. Insufficient erythrocytes to carry O2 to peripheral tissues. Symptoms:. Tachycardia, DOE, decreased exercise . tol. , . pallor. . depend on severity and acuity. Anthony Winchell. What is Fanconi Anemia?. http://www.sitemaker.umich.edu/nhowlett/files/fa-qr.gif. What is the Fanconi Anemia pathway?. http://www.hindawi.com/journals/anemia/2012/926787/. What is Fanconi Anemia Complementation Group L?. Anemia:. Deficiency of hemoglobin in the blood.. Causes: . Too few RBCs.. Too little hemoglobin in cells. Decreased packed cell volume.. This may be due to. :. decreased production of RBCs.. increased destruction.. Hemolysis. is defined as the premature destruction of red blood cells (RBCs).. Anemia results when the rate of destruction exceeds the capacity of the marrow to produce RBCs. Normal RBC survival time is 110. Mohammad Asgar Khan, MD. Anemia. Learning Objectives:. Learn the pathophysiology of anemia in CKD.. Learn the diagnostic challenges of anemia in CKD.. Learn the therapeutic strategies and related controversies in the treatment of anemia in CKD.. CKD . Patients. 2012 KDIGO . Update. Dr. . Shahram. . Taheri. . CKD is a worldwide public health issue. . The incidence and prevalence of kidney failure are increasing, outcomes are poor, and the cost is high. . red blood cell mass . or . blood hemoglobin concentration. . In practice, anemia most commonly is defined by reductions in one or both of the following:. Hematocrit (HCT) – The HCT is the fractional volume of a whole blood sample occupied by RBCs, expressed as a percentage. As an example, the normal HCT in a child age 6 to 12 years is approximately 40 percent.. a sign . of an underlying . disorder. There are several kinds of anemia. . A. . physiologic . approach classifies anemia according to whether. the deficiency in erythrocytes is caused by a defect in . referance. range for the age and sex. The normal ranges vary with age . -neonate < 14g/dl. -1-12mths < 10mg/dl. -1-12y< 11 g/dl. Causes of anemia can be from. Reduced cell production. Increased destruction. .. Epidemiology.. Classification.. Review the terminology used to discuss anemia.. Evaluation:. .. . • Address clues in the history and exam that can direct the evaluation. . • Describe one approach to using lab tests to make the diagnosis. . April 2015 P Dr. Yoganathan. C Dissertation submitted to the Department of General Medicine P.S.G Institute of Medical Sciences & Research, Coimbatore CERTIFICATE BY THE GUIDE This is to certify that Department of internal medicine 1. with course of cardio-vascular pathology. Complete blood count (CBC). RED BLOOD CELL COUNT. M – 4,5-5,5 *10. 12. ; F – 3,5-4,5 *10. 12. . HEMOGLOBIN. M – 130-160 g/l (13-16 mg/dl); . COLLEGE OF MEDICINE. DEPARTMENT OF PATHOLOGY AND FORENSIC. Medicine. Dr. . Ala’a. . A.Razak. . Abood. Iraqi Board of . Haematopathology. Objectives. :. 1- Define microcytic anemia and give differential diagnosis of microcytosis..