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Clinicopathological Properties of Poorlydifferentiated Clinicopathological Properties of Poorlydifferentiated

Clinicopathological Properties of Poorlydifferentiated - PDF document

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Clinicopathological Properties of Poorlydifferentiated - PPT Presentation

639 6396462006 00001 and between those with solidand nonsolidmodel in patients with curative resection revealed that agetumor diameter depth of invasion lymphnode metastasisdifferentiate ID: 947766

patients solid survival type solid patients type survival table tumors differentiated curative year 302 rate figure typenon 558 registered

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639 : 639-646(2006) Clinicopathological Properties of Poorly-differentiated 0.0001), and between those with solid-and non-solid-model in patients with curative resection revealed that age,tumor diameter, depth of invasion, lymphnode metastasisdifferentiated or undifferentiated (solid-and non-solid-those with differentiated or solid-type tumor

s.However,there was no significant difference in the distribution of 641 Table I. The clinicopathological characteristics of all registered patients (n=1,558). VariablesDifferentiated-typeSolid-typeNon-solid-type (n=1118)(n=138)(n=302)70/446/67239/9973/229Male/Female829/28994/44171/131Presence/Absence54/106410/12841/261Presence/Absence45/107

38/1305/297Lower third4703885Middle third40561107Upper third2182864Entire251146Superficial70459106Well-defined1953042Ill-defined219491547266611050, 33152123100612069T16525465T22634280T3,420342157Presence/Absence375/74368/70202/100Presence/Absence546/57280/58232/70 Presence/Absence372/74666/72133/169 expanding-type tumors (10,11). In our pre

vious study (7),we did not detect a prognostic value of histologicaldifference in survival between patients with solid and 643 Figure 1. Disease-specific survival of registered patients (n=1,558). There was a significant difference in survival between patients with differentiated-(n=1,118) and non-solid-type tumors (n=302) (p)()(0001). Figure

2. tween patients withdifferentiated (n=990) and non-solid tumors (n=226) (p)()(001). between the solid-and non-solid-type was mainly due to the 645 patients with Solid-typeNon-solid-type (n)5-year survival rate (%)(n) 5-year survival rate (%) IB1793.82490.80.8407II2280.44279.80.6925III2171.97336.30.0480 IV333.32414.00.5947 Table IV.Prognos

tic factors assessed by multivariate analysis in patients receiving curative resection. VariablesCoefficientSEHazard ratio (95% CI)70/0.45040.15221.5690 (1.1643-2.1143)0.0031Tumor diameter (mm)0.002050 0.14390.17941.1547 (0.8124-1.6413)0.4225100/0.67860.20921.9711 (1.3081-2.9702)0.0012Depth of invasionT2/T11.73830.32465.6876 (3.0104-10.745

7)T3,4/T12.17630.34028.8132 (4.5244-17.1675)Lymph node metastasispN1/pN00.72820.22932.0714 (1.3214-3.2470)0.0015pN2/pN01.56680.23174.7912 (3.0425-7.5450)pN3/pN02.11360.26538.2779 (4.9214-13.9237)Non-solid/solid, differentiated0.22180.11201.3963 (1.1161-1.2483)0.0439 Present/Absent0.58490.17311.7948 (1.2784-2.5196)0.0007 Table V.Causes of deat

h in patients who underwent curative gastrectomy. DifferentiatedSolidNon-solid (n=174)(n=16)(n=75)Gastric cancer1121257Co-morbid disease27310Other cancers1812 Unknown1526 Table VI.Pattern of recurrence in patients who underwent curativegastrectomy. DifferentiatedSolidNon-solid (n=112)(n=12)(n=57)Peritoneal 42337Hematogenous58613 Lymphatic1237