PPT-Regulation of the Cell Cycle & Cancer

Chapter 11 p 206213 Chapter 12 p228243 Chapter 183 p373377 G 1 checkpoint G 1 G 2 G 2 checkpoint M checkpoint M S Control system Figure 1215 External Regulators. the Cell Cycle. 10.3. Regulating the Cell Cycle. Lesson Objectives. Describe how the cell cycle is regulated. .. Explain how cancer cells are different from other cells.. Controls on Cell Division . Dozens of proteins regulate the cell cycle.. Unit 5. Welcome Back! . Musical Chairs. TODAY:. Notes on Cell Cycle. Become medical school students on oncology . rotation. Homework for next time: Watch Bozeman video on cell cycle, mitosis and meiosis. There *may* be a quiz.. Page 250 & 251 . . 50 000 of the cells in your body will be replaced with new cells, all while you read this sentence.. Review of cell cycle. In . multicellular. organisms, . cells divide for . Why do cells need to divide?. Growth and development. You started as 1 cell and now you’re made up of roughly 40 TRILLION cells. Repair and regeneration of tissue. Reproduction. What happens when cells divide? . When Making New Cells . Goes Terribly . Wrong. Regulating the cell cycle. Not all cells move through the cell cycle . at the same rate. :. Most Muscle cells and nerve cells do not divide at all once they have developed. &. Cellular Division. I. Cell Division:. . All . cells. are derived from preexisting cells (Cell Theory) . Cell division . is the process by which cells produce new cells . I. Cell Division:. . Why is regulation of the cycle important?. 40%. Approximately 39.6 percent of men and women will be diagnosed with cancer at some point during their lifetime. . (based on 2010-2012 data). (cancer.gov). Unicellular organism- cell division reproduces . an entire . organism. Multicellular. organisms- cell . division . can . produce . growth or progeny. Cell . division functions in reproduction, growth, and repair. You Must Know. Ways that the cell cycle is regulated.. Ways in which the normal cell cycle is disrupted to cause cancer. . Concept 9.3: The eukaryotic cell cycle is regulated by a molecular control system. . Adake. . MD. Associate Professor . Department of Pharmacology. Yenepoya. Medical College. MANGALORE. . Introduction. Also . called . as anti . neoplastic. . drugs . or . cytotoxic. agents.. Cell . Growth Limitations. Surface area: Volume. Asexual vs Sexual Reproduction. Prokaryotic vs. Eukaryotic Cell Cycle. Binary Fission vs Interphase and Mitotic Phase. DNA, Chromosomes, Chromatin, Chromatids, Nucleosomes, Histones, Centromeres, Spindle, Centrioles, Parent/ Daughter cells. Cancer. Cancer affects approximately 9.6 million Americans. 1.4 million cases annually. 570,000 deaths annually. For persons younger than the age of 85, cancer is the leading cause of death in the United States since 1999. The Mitosis Puzzle. Lay blank sheet lengthwise .. Write Interphase, Prophase, Metaphase, Anaphase, & . Telophase. across the top of the sheet.. Cut out the cell diagrams and tape/glue them across the top under the appropriate phase label.. Alexey Khodjakov. Wadsworth Center. Genet. Mol. Biol. vol.22 n.4 São Paulo Dec. 1999. Karyotype of Pancreatic Cancer Cells. What do you notice that appears odd amongst these chromosomes? HINT: What should a normal karyotype look like? .