Paraoral structures1 DEPARTMENT OF ORAL PATHOLOGY AND MICROBIOLOGY Purpose Statement At the end of the lecture student should describe ID: 1047419
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1. Developmental Disturbances of Oral & Paraoral structures-1 DEPARTMENT OF ORAL PATHOLOGY AND MICROBIOLOGY
2. Purpose Statement At the end of the lecture student should describe-- genetic classification of various oral and paraoral disorders etiological factors in congenital developmental anomalies classification of oral and paraoral structures depending on location
3. Learning Objectives S.N.Learning Objectives Domain LevelCriteria Condition 1Enumerate clinical featuresCognitive Must KnowAll 2Write classificationCognitiveMust KnowAll3Write pathogenesisCognitive Must KnowAll 4Write radiographic featuresCognitive Must KnowAll 5Write histologic featuresCognitive Must KnowAll 6Enumerate differential diagnosisCognitive Nice to KnowAll 7Write treatment & prognosis Cognitive & PsychomotorMust KnowAll
4. ContentsIntroductionClassificationEtiological factors in congenital developmental anomalies Classification of developmental disturbances of oral and paraoral structures
5. Introduction DiseaseCongenital diseases- Diseases present at birthHereditary diseases- Diseases which are inheritedPrinciple of Dominance & Recessive Principle of segregation- Subsequent separation and reappearance of characters in the offspring & is a feature of inheritance
6. CLASSIFICATION Depending on the role of genetics, Witkop classified them asHeritable defects in dentition without generalized defectsHypoplasia of enamelHypocalcification of enamelHypomaturation of enamelPigmented hypomaturation of enamel
7. Local hypoplasia of enamelDentin dysplasiaDentinogenesis imperfecta Missing lateral incisors, third molars, cuspids, premolarsFused mandibular incisors Familial dentigerous cysts
8. Heritable defects in dentition with generalized defectsDentinogenesis imperfecta with osteogenesis imperfectaEnamel hypoplasia in vitamin D resistant ricketsEnamel hypoplasia with epidermolysis bullosa dystrophiaLocal hypoplasia of enamel with Fanconi syndrome
9. Missing teeth with anodontiaRetarded eruption with cleidocranial dystosisMissing lateral incisors with ptosis of eyelidMissing premolars with premature whitening of hair
10. Heritable defects in oral structures without generalized defects AnkyloglossiaElephantiasis gingivaeHarelip Harelip with cleft palate
11. Heritable defects of oral structures with generalized defectsAlveolar bone changes in sickle cell diseaseGingival hemorrhage in hemophilia and Christmas diseaseOral hematomas with Ehlers Danlos syndromeMicrognathia with Pierre Robin syndromeNeurofibroma and pigmentation in neurofibromatosis
12. Hypercementosis in paget’s diseaseCircumoral pigmentation with gastrointestinal polyposisFacial deformity in gargoylismWhite spongy nevus of mucous membraneOsteosclerosis in Albers Schonberg diseaseHypoplasia of maxilla with achondroplasiaPeriodontitis with agammaglobulinemia
13. Etiological factors in congenital developmental anomalies Genetic factors InheritedMutagenic Environmental factorsPhysical injuriesPressure, Temperature changes, RadiationsHormonesACTH, Cortisone, Diabetes mellitus, Hyperthyroidism, Hypothyroidism
14. NutritionDeficiencies of Vitamin A, B1, B2, B6, Niacin, Folic acid, B12,D, E,K, Proteins, Amino acids, Potassium, Hypervitaminosis A RespirationHypoxia, Carbon dioxide excess, Carbon monoxide, Gaseous Anesthesia Drugs & ChemicalsSalicylates, Quinine, Tetracyclines, Thalidomides, Pilocarpine, Boric acid, Nicotine, Chloroquine, Sulfanomaides, Selenium, Trypan blue
15. Maternal diseases and defectsUterine tumors, Uterine inflammation, Uterine malformation, Defects in implantation, Age, Emotional disturbances, Stress, multiple pregnancies Embryonic defects Abnormalities of the ovum, Abnormalities of the semen, Antigen- Antibody reaction
16. Classification of developmental disturbances of oral and paraoral structuresDevelopmental Disturbances of JawsAgnathiaMicrognathiaMacrognathiaFacial hemihypertrophyFacial hemiatrophyAbnormalities of dental arch relations.
17. Developmental Disturbances of Lips and PalateCongenital lips and commissural pits and fistulaDouble lipCleft lip and palateCheilitis glandularisChelitis granulomatosaHereditary intestinal polyposis syndromeLabial and oral melanotic macule.
18. Developmental Disturbances of Oral MucosaFordyces granulesFocal epithelial hyperplasia (Heck's disease)Developmental Disturbances of GingivaFibromatosis gingivae Retrocuspid papilla.
19. Developmental Disturbances of the TongueMicroglossia MacroglossiaAnkyloglossia Cleft tongue Fissure tongue Median rhomboid glossitis Benign migratory glossitis Hairy tongue Lingual varices Lingual thyroid nodule.
20. Developmental Disturbances of Oral Lymphoid Tissue Reactive lymphoid aggregates Lymphoid hamartoma Angiolymphoid hyperplasia with eosinophils Lymphoepithelial cyst.
21. Developmental Disturbances of Salivary GlandsAplasiaXerostomiaHyperplasia of palatal glandAtresiaAberrancyDevelopmental mandibular salivary gland depression.
22. Developmental Disturbances of Size of Teeth Microdontia Macrodontia.Development Disturbances in Shape of TeethGeminationFusionConcrescence Dilaceration Talon's cusp Dens in dente Dens evaginatus Taurodontism Supernumerary roots.
23. Developmental Disturbances in Number of TeethOligodontia AnodontiaSupernumerary teeth Predeciduous dentition Post permanent dentition.
24. Developmental Disturbances in Structure of TeethAmelogenesis imperfecta Dentinogenesis imperfecta Dentin dysplasia Regional odontodysplasia Dentin hypocalcification.
25. Disturbances of Growth (Eruption) of TeethPremature eruption Delayed eruption Multiple unerupted teeth Embedded and impacted teeth Ankylosed teeth.
26. Fissural (inclusion, developmental) Cyst of Oral RegionMedian maxillary cystMedian palatal cystGlobulomaxillary cystMedian mandibular cystNasoalveolar cystPalatal cyst of the neonateThyroglossal tract cystBenign cervical lymphoepithelial cystDermoid and epidermoid cysts.
27. SUMMARY By the end of the lecture student should be able to understand the genetic classification of various oral and paraoral disorders etiological factors in congenital developmental anomalies classification of oral and paraoral structures depending on location
28. BibliographyShafer’s text book of oral pathology 5th & 6th editionOral and maxillofacial pathology Neville, 2nd editionColor atlas of oral diseases Cawson, R. A. 8th edition
29. THANK YOU!