PPT-BioCyc: "Big Knowledge" of Genomes and Metabolic Pathways

Peter D Karp ecocycorg SRI International biocycorg metacycorg BioCyc Overview Integrates diverse data and knowledge for thousands of genomes Curated and computationally generated. . Kinds of Web Services. Data retrieval Web Services. PTools. -XML. BioPAX. Visualization Web Services. Overview highlights. Generating pathway images. Adding . omics. data to overviews or pathways. METABOLIC ALTERATIONS TO THE MUCOSAL MICROBIOTA OF INFLAMMATORY BOWEL DISEASE PATIENTS ARE ASSOCIATED WITH CD4+ T CELL HOMEOSTASIS . Michael Davenport, Jordan Poles, Jacqueline Leung, Martin J. Wolff, . Clinical Chemistry Unit Pathology Department. College of Medicine, KSU. Objectives. By the end of the lecture, students are expected to:. Define a metabolic pathway.. Describe the general metabolic pathways for glucose (production and utilization). (a). Revise your knowledge on the properties of enzymes. State what is meant by metabolism and metabolic pathway. State what is meant by an anabolic pathway (and make reference to energy). State what is meant by a biosynthetic reaction. (e). Describe the action of competitive inhibitors. Describe the action of non-competitive inhibitors. Describe the action of feedback inhibition. Describe and identify the impact of each of the above on the rate of reaction and through a graph of results. Dr Anissa Atif Mirza. What is Metabolism?. Metabolism is a . network of metabolic /biochemical reactions.. Carried out in living cells.. In a. well organized, integrated and regulated manner.. Related to various biomolecules viz. What you should learn:-. The difference between . Anabolic. and . Catabolic. metabolic pathways, and give examples of each.. The importance of . reversible, irreversible . and . alternative. pathways in the control of metabolism.. Through Epigenetic Changes? * Lian Sidorov Matti Pitkanen Kean Hin Ooi E - mail: liansidorov@gmail.com Abstract: Based on preliminary reports, case studies (Roy, 2000; Yan et al., 2002b) a s well as Through Epigenetic ChangesLian SidorovMatti PitkanenKean Hin OoiE-mail liansidorovgmailcomAbstractBased on preliminary reports case studies Roy 2000 Yan et al 2002b as well as an in vitro experimen Biomolecular Chemistry Department School of Medicine and Public Health University of Wisconsin The Denu laboratory has investigated the mechanism and biological function of reversible protein • Be able to describe the various modes of regulation of metabolic pathways as they are presented in this lecture.. • Be able to explain the key properties of coenzymes, and know the types of group carried by each coenzyme discussed in this lecture.. Coenzyme A (CoA) is made up of several components: pantothenic acid (vitamin B. 5. ), phosphorylated ADP, and . aminoethanethiol. .. Learning Goal . Describe the components and functions of the coenzymes NAD. Steven Hallam | University of British Columbia. SRI International, 2013. Overview. Through the looking glass…. Environmental Pathway/Genome Databases. MetaPathways. Pipeline Development. 2. Metabolism. Microbial Genomes Web Portal. Peter D. Karp . ecocyc.org. SRI International . biocyc.org. . metacyc.org. . SRI International. A nonprofit multi-disciplinary research institute.