PPT-Adrenergic receptors Dr. S. Parthasarathy

Adrenergic receptors Dr S Parthasarathy MD DA DNB MD Acu Dip DiabDCA Dip Software statistics Ph d Mahatma Gandhi Medical college and research institute puducherry. Dr. S. Parthasarathy . MD., DA., DNB, MD (. Acu. ), . Dip. Diab.DCA, Dip. Software statistics . PhD (. physio. ). . Mahatma . gandhi. medical college and research institute, . puducherry. , India. SYSTEM. . . TWO MAJOR DIVISIONS. PARASYMPATHETIC. -ganglia close to organ innervated. -. preganglionic. fibers are . myelinated. and long. -postganglionic fibers short and . unmyelinated. SYMPATHETIC. By Linda Self. NUR 3703. Divisions of human nervous system. Nervous system. Sympathomimetic or adrenergic in sympathetic nervous system—neurotransmitters are ____________. Parasympathomimetic or cholinergic are used to describe parasympathetic system—neurotransmitter is _____________. OBJECTIVES. 1. Know anatomical organization of ANS.. 2. Discuss the synthesis, storage, release,. actions and degradation of . adrenergic . 3. Explain . adrenergic. transmission. 4. Discuss . Structure activity relationship (SAR)of sympathomimetic amines, Adrenergic antagonist and Neurone blockers Dr. ISHOLA I.O. PHARMACOLOGY, THERAPEUTICS AND TOXICOLOGY CMUL INTRO Phenylethylamine can viewed as parent compound, NA, AD, DA, ISOP Adrenalin, Noradrenalin. Sympathomimetics (direct & indirect). Sympatholytics. Adrenergic Receptors. Removal of Norepinephrine. Diffuse out of the synaptic cleft. Metabolized by COMT. Reuptake into the neuron. Adrenergic . Agents. Assist . Prof . Karima F. Ali. AL-Mustansiriyah university. College of pharmacy. Adrenergic drugs. . exert their principal pharmacological . and therapeutic . effects by either enhancing or reducing . Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. The . impulse transmission that is mediated by norepinephrine (post-ganglionic sympathetic nerve terminals and CNS), dopamine (CNS) and epinephrine (adrenal medulla) is in general called as adrenergic transmission. All these transmitters are also called as . ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. These are drugs which mimic the effects of sympathetic stimulation or those of . sami. Cardiac Output (CO). CO =HR X stroke volume (SV). SV: is the amount of blood ejected from the ventricles with each beat – average is . approx. 70mls. SV is affected by . preload. , . contractility. . Dr. . Zahraa. M. . Ayad. Al-. mustaqbal. . University College. Department of . Nursing . 2. nd. Class. . Pharmacology /2. nd. semester. Adrenergic drugs (Sympathomimetic). Adrenergic drugs stimulate adrenergic receptors, thereby activating the sympathetic nervous system and inducing symptoms characteristic of the fight-or-flight response (sympathetic stimulation).. Objectives. Discuss the pharmacology of . catecholamines. Classify & describe adrenergic α-agonists including actions, therapeutic uses & adverse. reactions.. Classify & describe adrenergic β-agonists including actions, therapeutic uses & adverse. Prepared by . Dr . zainab. . eltrafi. Clinical pharmacist. Sympathomimetic amines that contain the 3,4-dihydroxybenzene group (such as epinephrine, norepinephrine, isoproterenol, and dopamine). are called catecholamines. . .. Adrenomimetics. - it is drugs that imitate the action of . noradrenaline. (NA) in the adrenergic synapses and cause the sympathetic effects on internal organs.. Thus, the main "target" action agonists is adrenergic synapse, which has certain structural and functional features..