PPT-Adrenergic drugs By : Lec

Dr Zahraa M Ayad Al mustaqbal University College Department of Nursing 2 nd Class Pharmacology 2 nd semester Adrenergic drugs Sympathomimetic Adrenergic drugs stimulate adrenergic receptors thereby activating the sympathetic nervous system and inducing symptoms characteristic of the fightorflight response sympathetic stimulation. Adrenergic Antagonists. Adrenergic Antagonists. Cause direct blockade of adrenergic receptors. With one exception, all produce reversible (competitive) blockade. Most adrenergic antagonists are more selective than the adrenergic agonists.. Chapter 13, . Stryer. Short Course. Signal Transduction. Signal from exterior of cell must affect interior of cell. Through the membrane. Amplification of signal. Ability to turn off. A few pathways…. β-adrenergic antagonists are commonly used to treat hypertension, angina, tremor, migraine, and panic attacks.. ACTION. β-adrenergic antagonists competitively antagonize the effects . of . catecholamines. Def: The ANS consists of all visceral motor neurons innervating smooth muscle, cardiac muscle and glands.. Divide Autonomic Pharmacology into Four Categories:. 1. Drugs that increase the sympathetic nervous system response . Adrenergic receptors Dr. S. Parthasarathy MD., DA., DNB, MD ( Acu ), Dip. Diab.DCA, Dip. Software statistics- Ph d Mahatma Gandhi Medical college and research institute , puducherry Adrenalin, Noradrenalin. Sympathomimetics (direct & indirect). Sympatholytics. Adrenergic Receptors. Removal of Norepinephrine. Diffuse out of the synaptic cleft. Metabolized by COMT. Reuptake into the neuron. Classify adrenergic antagonists . Describe actions, therapeutic uses & adverse effects of adrenergic antagonist.. b. Discuss the role of autonomic drugs in central nervous system disorders. c. Enlist drugs used in glaucoma. Adrenergic . Agents. Assist . Prof . Karima F. Ali. AL-Mustansiriyah university. College of pharmacy. Adrenergic drugs. . exert their principal pharmacological . and therapeutic . effects by either enhancing or reducing . Calcium Channel Blocker. WASU TACHAWATTANAKUL, M.D.. Objective. Pharmacologic properties of beta-adrenergic antagonist & calcium channel blocker. Clinical manifestation. Management & Antidote. Part 1. . Thomas E. Tenner, Jr., Ph.D.. Dept. of Medical Education. Dept. Pharmacology & Neuroscience. tom.tenner@ttuhsc.edu. 743-7169. 1. Recommended Background Reading :.  . Chapter 6. “Introduction to Autonomic Pharmacology” . ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. These are drugs which mimic the effects of sympathetic stimulation or those of . ICU: Intensive Care Unit. J Investig Allergol Clin Immunol 2010; Vol. 20, Suppl. 1: 27-31 adrenergic agonists; b) the patient was already requiring oral glucocorticoids. The daily dose is 0.5 to 1 mg sami. Cardiac Output (CO). CO =HR X stroke volume (SV). SV: is the amount of blood ejected from the ventricles with each beat – average is . approx. 70mls. SV is affected by . preload. , . contractility. . Symaptholytics. Sensitivity of receptors. Two Families:. Alpha and Beta. Based on affinity to adrenergic agonists. Alpha affinity:. epinephrine. ≥norepinephrine. >> . isoproteranol. Beta affinity:.