PPT-PROF. A. K. SAKSENA ADRENERGIC RECEPTORS AND DRUGS

ADRENERGIC RECEPTORS α 1 α 2 Postsynaptic Presyn periphery Sm M of peripheral BV NT release . Pharmacology 49.222. Bill Diehl-Jones RN, PhD. Faculty of Nursing and Department of Zoology. Agenda. A Zen Review. Overview of CNS and ANS. Neurotransmitters and 2. nd. Messengers. Cholinergic Agonists and Antagonists. SYSTEM. . . TWO MAJOR DIVISIONS. PARASYMPATHETIC. -ganglia close to organ innervated. -. preganglionic. fibers are . myelinated. and long. -postganglionic fibers short and . unmyelinated. SYMPATHETIC. α. ADRENOCEPTOR ANTAGONISTS. Phenoxybenzamine. ,. Phentolamine. , . Tolazoline. , Ergotamine. , DHE, . Ergotoxine. Yohimbine. (. α. 2. ). Non-selective older drugs; Block both . α. 1. & . α. Def: The ANS consists of all visceral motor neurons innervating smooth muscle, cardiac muscle and glands.. Divide Autonomic Pharmacology into Four Categories:. 1. Drugs that increase the sympathetic nervous system response . By Linda Self. NUR 3703. Divisions of human nervous system. Nervous system. Sympathomimetic or adrenergic in sympathetic nervous system—neurotransmitters are ____________. Parasympathomimetic or cholinergic are used to describe parasympathetic system—neurotransmitter is _____________. Adrenergic receptors Dr. S. Parthasarathy MD., DA., DNB, MD ( Acu ), Dip. Diab.DCA, Dip. Software statistics- Ph d Mahatma Gandhi Medical college and research institute , puducherry Nervous System. Part 2. . Thomas E. Tenner, Jr., Ph.D.. Dept. of Medical Education. Dept. Pharmacology & Neuroscience. tom.tenner@ttuhsc.edu. 743-7169. 1. Recommended Background Reading :.  . Chapters 7, 8, 9, and 10 . Adrenergic . Agents. Assist . Prof . Karima F. Ali. AL-Mustansiriyah university. College of pharmacy. Adrenergic drugs. . exert their principal pharmacological . and therapeutic . effects by either enhancing or reducing . Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. The . impulse transmission that is mediated by norepinephrine (post-ganglionic sympathetic nerve terminals and CNS), dopamine (CNS) and epinephrine (adrenal medulla) is in general called as adrenergic transmission. All these transmitters are also called as . Sympatholytics. ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. These . ). Dr.. . Nirbhay. Kumar. Asstt. . Professor & Head. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. These are drugs which mimic the effects of sympathetic stimulation or those of . sami. Cardiac Output (CO). CO =HR X stroke volume (SV). SV: is the amount of blood ejected from the ventricles with each beat – average is . approx. 70mls. SV is affected by . preload. , . contractility. . Dr. . Zahraa. M. . Ayad. Al-. mustaqbal. . University College. Department of . Nursing . 2. nd. Class. . Pharmacology /2. nd. semester. Adrenergic drugs (Sympathomimetic). Adrenergic drugs stimulate adrenergic receptors, thereby activating the sympathetic nervous system and inducing symptoms characteristic of the fight-or-flight response (sympathetic stimulation).. .. Adrenomimetics. - it is drugs that imitate the action of . noradrenaline. (NA) in the adrenergic synapses and cause the sympathetic effects on internal organs.. Thus, the main "target" action agonists is adrenergic synapse, which has certain structural and functional features..