PPT-Diagnosis and management of acute myeloid leukemia in children and

adolescents recommendations from an international expert panel BFM blood 2012 120 31873205 Absence of published recommendations specific for pediatric AML motivated an international . Farhad. . Ravandi. , . MD. Professor of Medicine. University of Texas MD Anderson Cancer Center. Disclosure of Conflicts of Interest. Dr. . Ravandi. discloses that he is a consultant/advisor for Pfizer, . Rebecca L. King, . Gerald Wertheim, Michele E. Paessler. The Children’s Hospital of Philadelphia. Perelman School of Medicine at the University of Pennsylvania. Philadelphia, PA. Clinical History. 13 year old boy. C. linical Perspective. Mary Ward, RN, BS, CTR. Objectives. To increase the Cancer Registrar’s knowledge of the disease process of select cancers of the bone marrow from a clinical perspective. Discuss the pathogenesis, clinical evaluation and treatment options of AML, APL, MDS and Multiple Myeloma . Dr. . B.V.Vydehi. M.D. PROFESSOR OF PATHOLOGY. NARAYANA MEDICAL COLLEGE,NELLORE. Uncontrolled & abnormal proliferation of one of white blood cells & their precursors in the bone marrow and peripheral blood. Geoff Cuvelier MD FRCPC. Pediatric Oncologist. CancerCare. Manitoba. Associate Professor, . Dept. of Pediatrics and Child Health. University of Manitoba. Canadian Association of Physician Assistants Conference . Justyna Rybka. Department of . Haematology. , Blood Neoplasms and Bone Marrow Transplantation. Wroclaw Medical University. Klinika Hematologii, Nowotworów Krwi. i Transplantacji Szpiku . AML is a heterogeneous haematological malignancy of the myeloid blood cells. PROGNOSTIC FACTORS. Although the first published reports of leukemia occurred in 1845 by Bennett and Virchow, the lack of refined diagnostic methodology limited the distinction between myeloid and lymphoid acute leukemia, With the development of refined staining techniques, followed by microscopy and histochemical staining by the mid-20th century, this distinction was . BSW00073 / OK 11 - ONC - 152 1 July , 2011 Fact Sheet Leukemia is a cancer that begins in the bone marrow ( the soft inner part of some bones), but in most cases, moves into the blood. It can t hen s ental College (JIMDC); 201 3 ;2 ( 4 ): 58 - 63 58 Original Article Acute Myeloid Leukemia amongst Adults Naghmi Asif 1 and Khalid Hassan 2 1 Assistant Professor, Department of Pathology, Islamabad Me Medical Science Erythroleukemia with Complex Cytogenetic Abnormalities: A case report with review of literature Pooja K SureshPurnima S RaoUrmila N KhadilkarDepartment of Pathology, Kasturba Medical C Sofia Kolovich. 1. , Allison LaRocco. 1. , . Malith. Karunasiri. 1. , Girish Rajgolikar. 1. , Allison Walker. 1. , Ramiro Garzon. 1. , Marius Bill. 1. , Adrienne Dorrance. 1. . 1. The Ohio State University Comprehensive Cancer Center, Division of Hematology, The Ohio State University, Columbus, OH 43210.. Goals. Incidence. Etiology. Diagnosis. Types/Classification. Treatment. Primary Care Pearls. Incidence. 30% of all cancers in childhood. Peak incidence 2-5 years of age. males > females. Caucasian > African American. . A. ccumulation of abnormal blasts (. I. mmature precursors of WBC). . in bone marrow and blood leading to:. . 1- Bone marrow failure. . (. anemia ,neutropenia & thrombocytopenia). . 2- Organ infiltration . Jayllex Mills,. PharmD Candidate. AML Background. Hematologic malignancy affecting the blood and bone marrow. Result of proliferation of abnormal myeloid stem cell derivatives and interference of normal blood cell production.