hours to or more SMITH 1962b SMITH 1964 INTERSCAPULAR SUBCUZ VENTRAL SUBCUT 0 0 L7 I 0 brown adipose tissue during coldinduced arousaI deep hibernation of brown SMITH ID: 938383
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of Physiology, Univ. of California, Los Angeles, die einer Umgebungstemperatur ausgesetzt werden, steigt die braunen Fetts hours to or more (SMITH 1962b, & SMITH 1964). INTERSCAPULAR SUBCUZ VENTRAL SUBCUT. 0 0 .~L/___..~7~. [~.~, - I 0 , , brown adipose tissue during cold-induced arousaI deep hibernation. of brown & SMITH 1964). First it 2, a responses in !4.:." N , . ~ , , . " Fig. 2: adult rat kept × 7
50. of further H 3 / ~ 0 , Fig. 3: exhibiting synthesis various times the host to cold the end H a were not animals the were found foregoing, histological were conducted this tissue gressive rise exposure time; hence the exposure to Fig. 4). & RO~I;RTS I I I I I t I I t 0 I I I I I I I 4: Numbers adipose celis male rats Braeh. B.F. ,;' • o I J 1 J i I i I i 0 1 2 $ 4 5 6 7 8 adipose tissue major site
s growth of peak of hours was & GREULICH) O I I I I I I I I t ~ t t 1 I I I I O t 2 ~ 4 5 6 ? 8 9 14 15 16 TIME IN QO~ in with 0.05 M sucrose, 10; MgC12, 5; PO~ as KH2PO~I 37°C. Mean points, QO~ SMITI-I & ROBEWrs SMITH & cold acclimation weeks in in response the initial the initial intracellular multilocular seen also elsewhere in and neurohumorat Thus, in channels, these enhance the or three R. C., 1963
. Evidence an essentially constant duration synthesis in renewing epithelia 1964. Cytological responses tissue in cold Cell. Biol. (in press). A. T., 1924. 38, 147-205. R. & R., 1963. Thermogenic effect SmTH, R. E., the cold-acclimated 1962a. Thermoregutation adipose tissue Federation Proc. The physiological role adipose tissue. Proceedings Sci. Fenn. & HocK, R. J., 1963. Brown Thermogenic effector & HoIj~
R, D. J., 1962. Metabolism function in cold acclimation. C., 1964. Thermogenesis of brown adipose tissue cold-acclimated rats. this fine piece work. I severaI questions. To begin with, is the measurable changes obtained with locations, we the thermogenic a cold &allenge This response appears to be subject probably by nervous system. response different and adult evidence; however has shown satisfactory cold
3 months to a synergistic effect cortico-steroid action, shown (1953, also the cold resistance of neonatal there a between the metabolic rate? this question between thermogenic fat and aerobic metabolism, one this tissue. those which J. Physiol. has ascribed acyl phosphates anaerobic phase such animals Bull. Mus. considerable heats esterified triglycerides, acute cold exposure, aerobic reactions all of path
ways leading to either the direct generai these be expected to sympathetic adrenergic the cytoplasm. the tissue its high cold. Likewise increasing oxidase this tissue cold suggests close correlation between aerobic metabolism the response the season? SMrrm This question relates all of show considerable factors which are themselves seasonally such effects been recorded (see Jo~ANssoN 1959, ; Rr~iILLA~ 1958,
almost immediate different directions, probably at the cost of extra the grounds efficiency considerations, might have expected a somewhat sensitive compensatory mechanism. Maybe temperature patterns. has impressed us the extreme superior cervical these areas change temperatures opposite directions respective controls are possibly effector mechanisms. hinweisen, da~ das eine gro~e der plurivakuol~iren enth
~ilt. Nach Untersuchungen F. 2, 63-125) verschwindet dieses wiihrend der Geburt innerhalb bei einem - bei der zun~i&st freilich Zusammenhang zu bringen. This appears As we elsewhere, the adipose tissue this tissue (cf. (cf. R. E. discussion] ; Responses IV, 71). O2-Verbrauch (Energieproduktion) Menge der bere&net? Vers&iedene physiologische Gr/Sgen Wassergehalt, bei Bezug ist der weigem Fettgewebe glei&, ih
n auf dieses Bezugssystem berechnet. wissen, ob nach dem ersten Masse an st~indig erh6hte Aktivit~it wS.hrend Cytoplasma-Menge geleistet oder ob eine Ver- Cytoplasma-Masse erfolgt. ist also die Frage, ob geleistete Energieumsatz Gewebe, bezogen ist als SmTH: O~-consumption of wet reflects a both of with dramatic 140, 199) opening up vascular supply the general temperature at vascular returns from the perip