PPT-Previous Lecture: Motifs

Introduction to Biostatistics and Bioinformatics Phylogenetics This Lecture Learning Objectives Molecular Evolution Calculating Distances Clustering Algorithms Cladistic Methods . Today’s Topics In the previous lecture, we analyzed onedimensional motion, defining displacement, velocity, and acceleration and finding formulas for motion at constant acceleration. Today we Network Motifs and Modules. What is a motif?. A motif is a statistically over-represented . subgraph. in a network.. A pattern of connections that generates a characteristic dynamical response. A motif is a connection pattern template which could in principle be implemented.. Simon Andrews. simon.andrews@babraham.ac.uk. @. simon_andrews. v. 1.0. 1. Rationale. 2. Gene A. Gene B. Gene C. Hit A. Hit B. Hit C. Prom A. Prom B. Prom C. GGATCC. GGATCC. GGATCC. Basic Questions. Does the sequence around my hits look unusual?. John . McGuigan. 05/04/2009. Highly Conserved Elements. The most . conserved elements at least 200 . bp. long. Highly Conserved Elements are a much broader . set than UCEs. At least 200 . bp. long. Rachel Simpson. ADSHE Conference June 2013. POSSIBLE CAUSES. Gaps in Knowledge. Poor teaching in previous institution. Insufficient application on previous courses. Illnesses or absences from school/college. Contents page Contents page Previous page Previous page Previous page Understanding childhood immunisation D10550 December 2013 All information in this publication is correct at December 2013 Understa And the roots of Horror. Fiction Genre . Evolves over History. 1. Prose . 2. Novel . 3. Romance. Gothic (Terror). *. Horror . (. Slasher. , . Psychological. ,. scifi. , fantasy). Prose vs. Poetry. Define- Non- . Three Important Devices: Know These. Symbol: An object that represents something more significant that just itself. Motif: A . recurring. element or idea; a phrase; image; repetition of similar symbols; repetition of an issue/attitude. Elaine . Clavet. , Maria Gallo travailleuses sociales psychothérapeutes. Remue-Méninge. D’après vous, pour quelles raisons votre amie, collègue ou voisine aide-t-elle son père, son mari ou sa mère? . Cell Networks. University of Heidelberg. Interactions . and Modules: the how and why of molecular interactions. Proteins are modular. Since the early 1970s it has been observed that protein structures are divided into discrete elements or domains that appear to fold, function and evolve independently. . , . profileIndex. , . motifIndex. , . discordIndex. ] = . interactiveMatrixProfile. (data, . subLen. );. Input. data. : input time series. subLen. : subsequence length. Output. matrixProfile. : the approximated matrix profile when stopped. simon.andrews@babraham.ac.uk. @. simon_andrews. v. 1.0. 1. Rationale. 2. Gene A. Gene B. Gene C. Hit A. Hit B. Hit C. Prom A. Prom B. Prom C. GGATCC. GGATCC. GGATCC. Basic Questions. Does the sequence around my hits look unusual?. Motif 4. Motif 4. Motif 5. Motif 6. Supplementary . Figure . S2. . Amino acid sequence alignment of the five members of the Arabidopsis PAR1-family proteins (LAT1-5) shows a number of conserved regions and motifs throughout the protein sequence. Motifs were identified using Multiple . Deception-trickery, concealment of one’s feelings. Honor verses Shame-humiliation, violation of social expectations. Love- Romantic and Filial (Duty to family). Gender expectations- roles of men and women.