PPT-Network Motifs and Modules

Network Motifs and Modules What is a motif A motif is a statistically overrepresented subgraph in a network A pattern of connections that generates a characteristic dynamical response A motif is a connection pattern template which could in principle be implemented. 4 Tbps IO mid plane bandwidth Chassis Monitoring Module CMM with Integrated Lights Out Manager ILOM Hot swappable hot pluggable and redundant power supply and fan modules BENEFITS Foundation for the Sun Blade modular system integrating compute stora If your programme permits wild modules to be taken then you should refer to this document to help you select them Although you are free to apply for any module from the Wild Modules list including if you wish and if they are available further module 1 and Efficient Counting of Graphlets Yuval Shavitt School of Electrical Engineering shavitt@eng.tau.ac.il http://www.netDIMES.org http://www.eng.tau.ac.il/~shavitt Network Motifs: Why • Com and Lucia . Ramirez. Loyola Marymount University . March 24, 2015. BIOL398-04: Biomathematical Modeling. Lee, T. I., Rinaldi, N. J., Robert, F., Odom, D. T., Bar-Joseph, Z., Gerber, G. K., Hannett, N. M., Harbison, C. T., Thompson, C. M., Simon, I., Zeitlinger, J., Jennings, E. G., Murray, H.L ., Gordon, D. B., Ren, B., Wyrick, J. J., Tagne, J. B., Volkert, T. L., Fraenkel, E., Gifford, D. K. & Young, R. A. (2002). Transcriptional regulatory networks in Saccharomyces cerevisiae. Science, 298(5594), 799-804. DOI: 10.1126/science.1075090. By Toni Morrison. Written in:.  New York: 1962–1965. First published in 1970. Setting:. Set in 1941 in Lorain, Ohio, Toni Morrison's novel centers on a particularly difficult year in the life of eleven year old Pecola Breedlove.  Pecola comes from a poor and poorly adjusted black family. . Brief History:. 1998 – Foundation in October – started with simple E1 . interface converters. 1999 – Started project of . DmView. Network Management . System. 2000 – Launch of E1 multiplexer, first more complex product. . Cell Networks. University of Heidelberg. Interactions . and Modules: the how and why of molecular interactions. Proteins are modular. Since the early 1970s it has been observed that protein structures are divided into discrete elements or domains that appear to fold, function and evolve independently. . Sushmita Roy. sroy@biostat.wisc.edu. Computational Network Biology. Biostatistics & Medical Informatics 826. Computer Sciences 838. https://compnetbiocourse.discovery.wisc.edu. Nov 1. st. 2016. Some material is adapted from lectures from Introduction to Bioinformatics. Cody Dunne and Ben Shneiderman. {cdunne, ben}@. cs.umd.edu. 30. th. . Annual . Human-Computer Interaction Lab Symposium, May 22–23, 2013. College Park, . MD. Who Uses Network Analysis. Network Analysis is Hard. 590AI. Some content from . Lada. . Adamic. Vocabulary Lesson. Actor. Relational Tie. parentOf. supervisorOf. reallyHates. ( /-). …. Dyad. Person. Group. Event. …. Relation. : collection of ties of a specific type (every . simon.andrews@babraham.ac.uk. @. simon_andrews. v. 1.0. 1. Rationale. 2. Gene A. Gene B. Gene C. Hit A. Hit B. Hit C. Prom A. Prom B. Prom C. GGATCC. GGATCC. GGATCC. Basic Questions. Does the sequence around my hits look unusual?. Network motifs. Network clusters / modules. Co-clustering networks & expression. Network comparison. (species, conditions). Integration of genetic & physical nets. Network visualization. Network. Ron Shamir. School of Computer Science. Tel Aviv University. April 2013. 1. Sources: . Igor Ulitsky and Ron Shamir. Identification of Functional Modules using Network Topology and High-Throughput Data. BMC Systems Biology 1:8 (2007). . Chemical. . Modifications. Dr. Hilal AY. Protein . motifs. . and. . domains. Protein motifs are small regions of protein three-dimensional structure or amino acid sequence shared among different proteins. .