PPT-In silico  evaluation of new fluoroquinolones as possible inhibitors of bacterial gyrases

Manuel Alejandro CobaMales 1 Javier SantamaríaAguirre 2 and Christian D AlcívarLeón 1 1 Facultad de Ciencias Químicas Universidad Central del Ecuador Quito 170521 Ecuador macobauceeduec MACM cdalcivaruceeduec CDAL. Mark S. Johnson, . Pharm.D. ., BCPS. Associate Professor and Director of Postgraduate Education. Fluoroquinolones. Very popular class of antibiotics due to spectrum of coverage (gram positive, gram negative, . Quinolones. comprise of synthetic anti-bacterial agent, . naphthyridine. derivative introduced in the treatment of UTI.. Clinical usefulness of . quinolones. is due to good oral absorption, activity against gram negative urinary pathogens and comparatively higher concentration in urine than that of plasma or tissue conc. . Antibiotic Stewardship Program -ECHO. Update on Fluoroquinolones . Fluoroquinolone generations chart. Increased risk, greater than with most other antibiotics, for causing . C. difficile . colitis . Acute Tendonitis. 4. th. class \biology department . The Antimicrobial agents . Sulpha. drug &. Quinolones. . Prepared by. . Dr.Sawsan. . Sajid. AL-. Jubori. Dr.Saad. L. Hammed . Sulfonamide.  (also called . Sciences GSAS login1Register for classes2Register for your RESI Unit3Access your billThe image to the right shows the Tuition and Fees Calculator Welcome screenTo use the RESI Unit will have theopport How when and where we work is redex00660069ningthe workplace And the best workspacesknow how to adapt Long-term successstems from balancing the individual needsof todays agile workforce To support the Jennifer Doan, pharm. D. Pharmacy resident, unity health. September 30, 2016. 1. Learning Objectives. Recognize potential fluoroquinolone toxicities that may occur with systemic fluoroquinolone use. Sulfonamides can be divided into three major groups: . (1) oral, absorbable; . (2) oral, . nonabsorbable. . (3) topical. . The oral, absorbable sulfonamides can be classified as short-, medium-, or long acting on the basis of their half-lives. Fernando . Durães . 1, 2. , . Ana Rita . Neves . 1, 2. , . Joana . Freitas-da-Silva . 2, 3. , . Annamária. . Kincses. . 4. , . Eugénia . Pinto . 2, 5. , . Paulo . Costa . 2, 3. , . Madalena . Pinto . methods to antimicrobial drug discovery . Dr Ricky Cain. Mathematics for Real-World Systems Summer School . 5. th. July 2016. What is Structure based drug discovery (SBDD). Virtual High-throughput Screening (vHTS). ACMG/AMP Variant . Interpretation . guidelines . (. Richards et al 2015). Population. Data. In . silico. Data. Segregation . Data. Database. Prevalence in . affecteds. statistically increased over controls. spatially resolved NK cell signaling model to interrogate . mechanisms of signal integration in human NK cells. Rajdeep. Kaur Grewal. 1. and . Jayajit. Das. 1,2. . 1. Abigail . Wexner. Research Institute at Nationwide Children’s Hospital, . Additional . findings from 2014 study . Vladimirs. . Strazdins. , MD. Riga, Latvia. May 9, 2018. Background. – . resistant. E.coli. Antimicrobial . resistance. (AMR) . is. . growing. . rapidly. …the . Antimicrobial agents . Fourth Lecture . 2022. Assist. Prof. Mohammed AboKsour. Sulfonamides . are synthetic antimicrobial agents . that . contain the . active antibacterial . sulfonamide.