Typically occur during meiosis gamete formation but can also occur during mitosis Can lead to cancer some cases We will look at Translocation Deletion Duplication and Inversion Few harmful gene mutations are passed on to the next generation because the zygote usually dies If it lives the o ID: 1000018
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1. Chromosomal Mutations
2. Affects an entire chromosome or chromosomesTypically occur during meiosis (gamete formation) but can also occur during mitosisCan lead to cancer some casesWe will look at: Translocation, Deletion, Duplication and InversionFew harmful gene mutations are passed on to the next generation because the zygote usually dies. If it lives, the offspring may have birth defects.Chromosomal Mutations
3. Deletion of part of a chromosome - Genetic Material Breaks OffDeletionA B C D E F G HA B C E F G HGene “D” has been deleted
4. Duplication of Part of a Chromosome – Extra Copies of a Gene are GeneratedB and C were duplicated A B C D E F G HA B C B C D E F G H
5. Inversion - Part of A Chromosome Breaks Off and Reattaches Backwards B, C and D Inverted to Become D, C and B A B C D E F G H A D C B E F G H
6. Translocation - Part of One Chromosome Breaks Off and Attaches to a Different ChromosomeABEFDCBXAWCHGGEHDFWXYZYZTranslocationOROr