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Abiomed  ELAB Meeting  March 3, 2017 Abiomed  ELAB Meeting  March 3, 2017

Abiomed ELAB Meeting March 3, 2017 - PowerPoint Presentation

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Abiomed ELAB Meeting March 3, 2017 - PPT Presentation

Ruth Fisher MBA Henry Ford Health System Vice President Heart and Vascular Services Detroit MI Detroit C ardiogenic S hock I nitiative Detroit CSI What is Detroit CSI How did we start ID: 1010716

shock detroit support heart detroit shock heart support news survival hospital treatment ford time attack cardiogenic patient cardiologists announce

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1. Abiomed ELAB Meeting March 3, 2017Ruth Fisher, MBAHenry Ford Health SystemVice President Heart and Vascular ServicesDetroit, MI

2. DetroitCardiogenicShockInitiative

3. Detroit CSIWhat is Detroit CSIHow did we startWhat are the resultsKey factors for our successHow to start in your market

4. This is what people think Detroit looks like

5. This is what Detroit really looks like

6. What Detroit really looks like

7. Henry Ford Health SystemFounded in 1915 by Henry Ford

8. Detroit CSI 5 competing hospitals systems8 participating hospital locations

9. DETROIT CARDIOGENIC SHOCK INITIATIVE DETROIT CSIDetroit Metro – 4.6M Population

10. What is Detroit CSIInitiative led by cardiovascular leaders at 5 competing hospitalsGoal to reduce mortality in Cardiogenic shock patientsDeveloped new Shock treatment protocol30 patient trial

11. How did we start?Visionary leader- 30 years in DetroitCreated a call to actionPartnered with Abiomed to help collect dataDr. William O’Neill, MD

12. Meeting of the familiesWe can do betterQuarterly meetings“Leave your ego at the door”Review current literature/dataCase discussionProtocol refinement

13. Mortality after onset of Shock

14. Basir, Dixon, O’Neill et al. AJC. 2017Early support leads to higher survival

15. Basir, Dixon, O’Neill et al. AJC. 2017Fewer inotropes - higher survival rates

16. Support first then PCI?

17. ProtocolHemodynamic support with device BEFORE PCI“Door to Support Time” trackedMeasure cardiac output before and afterReduce use of inotropes

18.

19. Pilot StudyJuly, 2016 – January, 2017N = 30Sites:St Joseph's Pontiac (N=10)Beaumont Royal Oak & Troy (N=9)Henry Ford (N=6)Detroit Medical Center (N=5)DemographicsAge 63 +/- 13 years (36-87)80% Male, 20% FemaleDiabetics 48%

20. Pre-Procedural CharacteristicsTransfer from outside hospital 31% (N=9/29)4 patient transported with IABP26% (N=8/30) In Hospital Cardiac Arrest23% (N=7/30) Required CPR67% presented to hospital in shock (N=19/28)

21. Procedural Characteristics 4 patients under active CPR at the time of Impella implantation75% survival (N=3/4)AMI to Shock Time (N=13)93 minutes100% Femoral AccessShock to Device Time (N=23)64.6 minutes (8-229)

22. OutcomesCardiac Power 0.56 (Pre) (n=15)0.90 (Post) (n=20)38% improvement in Cardiac Power Output38%

23. Survival Rates Pre and Post Study

24. CARDIOGENIC SHOCK A CHANGE IN PARADIGMDOOR TO BALLOON DOOR TO SUPPORT

25. News Conference Feb 8, 2017

26. News Conference

27. News ConferenceDetroit CSI team

28. Grateful patient

29. News Conference"This is exciting because for the first time in two decades, we've found a way to save lives" of cardiogenic shock patients, said Theodore Schreiber, M.D., president of the DMC Heart Hospital

30. Media HitsFox 2 TVTop metro Detroit cardiologists team up to test new heart pump  Detroit Free Press NewspaperDetroit hospitals see hope for heart attacks with new pump Crain’s Detroit Business Business News MagazineMetro Detroit cardiologists work together to improve heart attack survival rates Detroit NewsHealth systems: New heart attack treatment saving live WWJ RadioCritical Mention clip: WDIV RadioCardiologists announce results of 'successful effort to save lives'AP/Washington Times NewspaperCardiologists announce heart attack treatment initiative  WILX in Lansing TV Cardiologists announce heart attack treatment initiative

31. Key Factors to SuccessCompetitors who were willing to collaborateVisionary leaderExperienced and highly skilled interventionalists who were comfortable with the Impella deviceWilling to share their data Abiomed support

32. How to start a shock programDetermine level of experience and comfort with the Impella device in your marketDevelop a “team” Meeting of the “families”FellowAcute PCI coordinatorCVAD registry / data coordinatorInstitutional support Hub and spoke modelHospital/ cath lab/ administrationEducation

33. Questions