PPT-LEC4 genetic Dr. Eaman

Suud khalifa 2 Diseases caused by mutation in mitochondrial genes Mitochondria contain several genes encodes for enzymes of oxidative phosphorylation usually the ovum contain the large part of mitochondria so the inheritance of mitochondrial gene is maternal. Framework. Definition of re-contacting. Healthcare professionals’ (HCP) ethical responsibility/legal obligation to re-contact former patients about new genetic information.. Ethical responsibility/Legal duty. Genetic Variation . How can genetic diversity be increased?. How can genetic diversity be decreased?. List as many ways as you can think of. Learning Objectives. Understand what is meant by the ‘Founder effect’ and how it results in a loss of genetic diversity. Random change in allele frequencies from 1 generation to . the next.. Individuals who survive . & pass on their genes are not necessarily the “fittest” . Leads to a loss of genetic variation. Search and optimization method that mimics the natural selection. Terms to define. Chromosome – a set of . numbers representing one possible solution. Generation . – a single loop within GA loop search. Human chromosomes. Most cells in your body normally contain 46 chromosomes, organized into 23 pairs. In each of these 23 pairs, you've inherited one chromosome from your father and one from your mother. . Risks and Benefits of Knowing Your Genetic Makeup. Julie Hopp. Genetic Screening: Who Should Be Tested. CDC’s 2004 Science Ambassador Program. Overview. Genetics Review. Types of Genetic Disorders. You can compare dogs of every breed imaginable! . There is an enormous range of characteristics that are the result of . genetic variation. . . The differences among breeds of dogs are so great that someone might think that many of these breeds are different species. . 2. High. Risk. Medium Risk. Low Risk. Cost. Low. Medium. High. Used by. Universities. Companies & organizations. Military organizations. Vulnerability to attacks. High. Medium. Low. Security. Risk. The change in allele frequencies in populations due to . chance. (not selection). . Can include the loss of alleles from the gene pool.. Genetic drift. The change in allele frequencies in populations due to . . suud. . khalifa. Learning objectives:. Discuss . epidemiology&Risk. factors for Breast carcinoma. Carcinoma in . situ&their. types. Paget disease of the nipple. Pathological types of breast . khalifa. . Etiology of cancer . Many factors may play a role in etiology of cancer:.  . I. Geographical & environmental factors:. These factors . form about 65% of all cancer etiology, while genetic factor form about 26%- 42% of cancer etiology. What is the difference between . the mice in these two groups?. What is genetic engineering?. Genetic engineering is the . direct modification of an organism’s genome. , which is the list of specific traits (genes) stored in the DNA. . INDOLE ALKALODS. a class of . alkaloid.  containing . a structural moiety of . indole. ; many . indole. alkaloids also include.  . isoprene.  groups and are thus called . terpene. . indole. . or . . Suud. . khalifa. Diseases caused by mutation in structural proteins:. Marfan"s. syndrome:. . autosomal dominant disease of connective tissue (. fibrillin. ), both quantitative &qualitative defects have been noted..