PPT-Innate immunity in cardiology: vessel (coronary spasm) and

valve aortic stenosis MingYow Hung MD FACC Division of Cardiology Department of Internal Medicine Assistant Professor of Medicine Taipei Medical University Disclosure None Heart attack. It is sometimes called Prin zmetal angina and usually happens in people aged 50 years or younger Spasms can range from very minor to severe and sometimes may completely block your coronary artery CAS that is severe and lasts for more than 15 minutes Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. Present before exposure to pathogens. Present at birth. Non-antigen specific. Consists of:. Skin… barrier for microbes and viruses. Compromised by abrasion or laceration. Sebacious. sweat is acidic (pH 3-5)… prevents colonization of bacteria. A. The body has two main mechanisms of defenses. 1. Innate defense mechanisms – first line of defense. A) These defenses are non-specific and . inherited. Immunity Overview. B) Examples:. 1. ) Physical barriers. Causes:-. Continuous . sever near work . in presence of refractive error.. Miotic such . as . pilocarpine. eye drop may bring spasm of CM.. Precipitating factors:-. Marked degree of . muscular imbalance . Cells of the Immune System. Physical & Chemical Barriers. Innate and Adaptive Immunity. Innate Defenses. Nonspecific physical and chemical barriers that contribute to resistance against infection. disease. Disease-any condition that impairs the normal functioning of the body. Violation of homeostasis. Homeostasis-ability of the body to keep proper internal conditions no matter what is happening outside of it. CC: Chest pain . 61 yr old male presented to ED w/ substernal. , non-radiating chest pressure . while walking that lasted approximately 30 minutes. . . Bilateral . arm numbness and . weakness. . Bilateral .  . Immunity . is defined as the capacity of the body to resist the pathogenic agents. It is the ability of the body to resist the entry of . different types of . foreign bodies like bacteria, . virus, . Learning objectives. By the end of this session student will be able to. . Define innate immunity, acquired immunity. . To understand cells involved in . innate . and acquired . immunity. IMMUNITY. Assis.Prof.Dr. . Suhad Faisal . Hatem. Innate immunity. . is considering first line of defense, an immediate response to a pathogen that does not confer lifelong protective immunity. It is includes :. of certain substances in . the blood and lymph stream. . These . substances are known as antibodies. . This immunity is inborn. . . Antigens. , the foreign substances that attack the body, stimulate the production of antibodies. . The resistance that an individual acquires during life by recognising and selectively eliminating specific foreign molecules is known as acquired immunity.. This is displays four characteristic features:.