PPT-Immunity – ( Innate and Acquired)

Learning objectives By the end of this session student will be able to Define innate immunity acquired immunity To understand cells involved in innate and acquired immunity IMMUNITY. . Ch.16. What is Immunity?. Immunity is resistance to infection after a foreign antigen has penetrated the first line of defense,. Immunity is achieved naturally, by having the disease or the artificial immunization. . Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. International . welcomes submissions that are original and technically so as to serve both the developing world and developed countries in the best possible way.. OMICS Journals are poised in excellence by publishing high quality research. . Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. Present before exposure to pathogens. Present at birth. Non-antigen specific. Consists of:. Skin… barrier for microbes and viruses. Compromised by abrasion or laceration. Sebacious. sweat is acidic (pH 3-5)… prevents colonization of bacteria. Clarence Lam, . Sanket. Patel, . Tairan. Yang, Narthaanan Srimurugathasan. PHM142 Fall 2016. Instructor: Dr. Jeffrey Henderson. Outline. Introduction and components of innate immunity. Differentiation from blood cells and mechanisms of phagocytosis. Immunology. - the study of host defense mechanisms. Immunity. -. ability of the host to protect itself against foreign organisms. Resistance to disease.. Antigen (Ag)- . is a foreign substance that can elicit specific immune response (IR) when is immunogenic. disease. Disease-any condition that impairs the normal functioning of the body. Violation of homeostasis. Homeostasis-ability of the body to keep proper internal conditions no matter what is happening outside of it. Dr. . Bipin. Patel. introduction. INTRODUCTION. The term “immunity” is referred to the . resistance of an individual . towards . injury. caused by . microbial stimuli . (microorganisms & their products) & . of certain substances in . the blood and lymph stream. . These . substances are known as antibodies. . This immunity is inborn. . . Antigens. , the foreign substances that attack the body, stimulate the production of antibodies. . The resistance that an individual acquires during life by recognising and selectively eliminating specific foreign molecules is known as acquired immunity.. This is displays four characteristic features:. An . acquired trait . is a . physical characteristic . that a living thing gets during its lifetime.. A scar is an example of a . physical. . trait. that is . acquired. .. Many acquired traits are . catherine. . hartnett. The Immune System. Concept 43.1- In innate immunity, recognition and response rely on shared traits of pathogens. Introductory Video. http://www.cleanvideosearch.com/media/action/yt/watch?v=Nw27_jMWw10. OA. OBJECTIVES. At the end of the lecture, students will be able to:. Explain the role of the immune system. Describe the two types of immunity. Explain antibodies and its various types. Define immunodeficiency.