PPT-Immunity – ( Innate and Acquired)

Learning objectives By the end of this session student will be able to Define innate immunity acquired immunity To understand cells involved in innate and acquired immunity IMMUNITY. . Ch.16. What is Immunity?. Immunity is resistance to infection after a foreign antigen has penetrated the first line of defense,. Immunity is achieved naturally, by having the disease or the artificial immunization. . Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. Present before exposure to pathogens. Present at birth. Non-antigen specific. Consists of:. Skin… barrier for microbes and viruses. Compromised by abrasion or laceration. Sebacious. sweat is acidic (pH 3-5)… prevents colonization of bacteria. A. The body has two main mechanisms of defenses. 1. Innate defense mechanisms – first line of defense. A) These defenses are non-specific and . inherited. Immunity Overview. B) Examples:. 1. ) Physical barriers. Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. Immunology. - the study of host defense mechanisms. Immunity. -. ability of the host to protect itself against foreign organisms. Resistance to disease.. Antigen (Ag)- . is a foreign substance that can elicit specific immune response (IR) when is immunogenic. Abbas. University of California San Francisco. FOCiS. Lecture outline. Components of innate immunity. Recognition of microbes and dead cells . Toll Like Receptors. NOD . Like Receptors/. Inflammasome. Dr. . M.A.Thomas. . FUNCTIONS . OF THE IMMUNE SYSTEM. :. Recognize. , destroy and clear a diversity of pathogens. .. Initiate . tissue and wound healing processes. .. Recognize . and clear damaged self components. Dr. . Bipin. Patel. introduction. INTRODUCTION. The term “immunity” is referred to the . resistance of an individual . towards . injury. caused by . microbial stimuli . (microorganisms & their products) & . of certain substances in . the blood and lymph stream. . These . substances are known as antibodies. . This immunity is inborn. . . Antigens. , the foreign substances that attack the body, stimulate the production of antibodies. . The resistance that an individual acquires during life by recognising and selectively eliminating specific foreign molecules is known as acquired immunity.. This is displays four characteristic features:. catherine. . hartnett. The Immune System. Concept 43.1- In innate immunity, recognition and response rely on shared traits of pathogens. Introductory Video. http://www.cleanvideosearch.com/media/action/yt/watch?v=Nw27_jMWw10. OA. OBJECTIVES. At the end of the lecture, students will be able to:. Explain the role of the immune system. Describe the two types of immunity. Explain antibodies and its various types. Define immunodeficiency.