PPT-Innate and adaptive immunity

AssisProfDr Suhad Faisal Hatem Innate immunity is considering first line of defense an immediate response to a pathogen that does not confer lifelong protective immunity It is includes . Lori Herrington. Chaparral High School. What is immunology?. Very simply, it is the study of our body’s defense against infection and disease.. Even though we are constantly bombarded by microorganisms, we rarely become sick. Why?. Chapter 22. Functions of the Immune System. Destroy pathogens (organisms that cause disease). Detect and kill abnormal cells such as cancerous cells. Remove dead cells and debris from the body. Pathogens. Adaptive (specific) Immunity. The general idea:. body . can recognize . specific. . invader and act to destroy . that specific invader.. Adaptive . immunity develops during an individual. ’. s lifetime.. Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. Present before exposure to pathogens. Present at birth. Non-antigen specific. Consists of:. Skin… barrier for microbes and viruses. Compromised by abrasion or laceration. Sebacious. sweat is acidic (pH 3-5)… prevents colonization of bacteria. Clarence Lam, . Sanket. Patel, . Tairan. Yang, Narthaanan Srimurugathasan. PHM142 Fall 2016. Instructor: Dr. Jeffrey Henderson. Outline. Introduction and components of innate immunity. Differentiation from blood cells and mechanisms of phagocytosis. A. The body has two main mechanisms of defenses. 1. Innate defense mechanisms – first line of defense. A) These defenses are non-specific and . inherited. Immunity Overview. B) Examples:. 1. ) Physical barriers. Learning objectives. By the end of this session student will be able to. . Define innate immunity, acquired immunity. . To understand cells involved in . innate . and acquired . immunity. IMMUNITY. Dr. . Bipin. Patel. introduction. INTRODUCTION. The term “immunity” is referred to the . resistance of an individual . towards . injury. caused by . microbial stimuli . (microorganisms & their products) & . Learning Objectives. Introduction to Immunity. Innate Immunity. Lymphoid Tissue. Introduction to Immunity. Immunitas. : Freedom from. Immunity is the ability of body to destroy potentially hazardous/harmful foreign substances, if entered in body, that is it provides FREEDOM from any foreign invader.. Principles . of Vaccination. : . Vaccination is one of the most effective medical interventions to reduce morbidity and mortality of infectious diseases. The main principle of vaccination is the proactive induction of a protective immune response by mimicking the natural interaction of an infectious pathogen (bacteria, viruses, etc.) with the human immune system (Fig 1). Immunostimulatory. and . fusogenic. liposomes (IFLs). . IFL may attract innate cells like DCs, macrophages leading to their . immunostimulation. and release of . proinflammatory. cytokines (pathway a). IFL may get . catherine. . hartnett. The Immune System. Concept 43.1- In innate immunity, recognition and response rely on shared traits of pathogens. Introductory Video. http://www.cleanvideosearch.com/media/action/yt/watch?v=Nw27_jMWw10. There are lots of . micoorganisms. that we . encounter everyday . through breathing, touching, and eating. . Most are detected and . destroyed within minutes or hours . by defense mechanisms that do not rely on the clonal expansion of antigen-specific lymhphocytes. .