PPT-Mechanisms of Innate Immunity

There are lots of micoorganisms that we encounter everyday through breathing touching and eating Most are detected and destroyed within minutes or hours by defense mechanisms that do not rely on the clonal expansion of antigenspecific lymhphocytes . Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. Evading the Immune response. Ryan Rego . Antibiotic . resistance: World on cusp of 'post-antibiotic era'. The world is on the cusp of a "post-antibiotic era", scientists have warned after finding bacteria resistant to drugs used when all other treatments have failed. . Evolutionary View. Epithelial barriers to infection. Four main types of innate recognition . molecules:TLRs. , CLRs, NLRs, RLRs. NF-. . B, the master transcriptional regulator of inflammation . Inflammation and recruitment of phagocytes. Present before exposure to pathogens. Present at birth. Non-antigen specific. Consists of:. Skin… barrier for microbes and viruses. Compromised by abrasion or laceration. Sebacious. sweat is acidic (pH 3-5)… prevents colonization of bacteria. • Lecture 1Defining Innate ImmunityRecognition and effector mechanisms (I)• Lecture 2Recognition and effector mechanisms (II)Integration of innate and adaptive immune responses http://www.br A. The body has two main mechanisms of defenses. 1. Innate defense mechanisms – first line of defense. A) These defenses are non-specific and . inherited. Immunity Overview. B) Examples:. 1. ) Physical barriers. Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. Learning objectives. By the end of this session student will be able to. . Define innate immunity, acquired immunity. . To understand cells involved in . innate . and acquired . immunity. IMMUNITY. Chapter 41 Key Concepts . 41.1 Animals Use Innate and Adaptive Mechanisms for Defense. 41.2 Innate Defenses Are Nonspecific. 41.3 Adaptive Defenses Are Specific. 41.4 The Humoral Adaptive Response Involves Antibodies. Abbas. University of California San Francisco. FOCiS. Lecture outline. Components of innate immunity. Recognition of microbes and dead cells . Toll Like Receptors. NOD . Like Receptors/. Inflammasome. Dr. . M.A.Thomas. . FUNCTIONS . OF THE IMMUNE SYSTEM. :. Recognize. , destroy and clear a diversity of pathogens. .. Initiate . tissue and wound healing processes. .. Recognize . and clear damaged self components. Dr. . Bipin. Patel. introduction. INTRODUCTION. The term “immunity” is referred to the . resistance of an individual . towards . injury. caused by . microbial stimuli . (microorganisms & their products) & . catherine. . hartnett. The Immune System. Concept 43.1- In innate immunity, recognition and response rely on shared traits of pathogens. Introductory Video. http://www.cleanvideosearch.com/media/action/yt/watch?v=Nw27_jMWw10. OA. OBJECTIVES. At the end of the lecture, students will be able to:. Explain the role of the immune system. Describe the two types of immunity. Explain antibodies and its various types. Define immunodeficiency.