PPT-WHO Thyroid Dose Estimation

f ollowing the Fukushima Daiichi NPP accident International Workshop on Radiation and Thyroid Cancer 22 February Tokyo JAPAN Outline WHO s mandate Firstyear dose estimation preliminary dose estimation report. Thyroid hormone regulates metabolism in both animals and humans Metabolism is determined by mea suring the amount of oxygen used by the body over a speci64257c amount of time If the measure ment is made at rest it is known as the basal metabolic rat Roy Shore, . Kyoji. Furukawa, . Misa. . Imaizumi. Radiation Effects Research Foundation. shore@rerf.or.jp. Atomic Bomb Survivor Study Overview. 2. A-bomb Study Characteristics. Life Span Study. Includes >86,000 survivors of all ages at exposure, with estimated doses and long follow-up for mortality (1950-2008) and cancer incidence (1958-2009). radioiodine(I-131) . intake for evacuees caused by the nuclear accident in Fukushima. S. . Tokonami. , M. . Hosoda . (. Hirosaki. . Univ. .). S. . Akiba. . (Kagoshima . Univ. .). INTRODUCTION. After nuclear accident in Fukushima on March 11. André Bouville. . (NCI, retired) and . Vladimir Drozdovitch (NCI). Workshop on Radiation and Thyroid Cancer. Tokyo, Japan, 22 February 2014. 1. Outline. Background information. Principles of dose reconstruction. INTRODUCTION. Thyroid rule:. In . a child, . critical for normal . growth and development. .. . In an adult, . maintain metabolic stability. . . Thyroid disorders result in . alterations in metabolic . V.K.. . Ivanov. Chairman, Russian Scientific Commission on Radiological Protection. . Medical Radiological Research Center . National Radiation and Epidemiological Registry. The International Workshop on . Introduction. . The prevalence of hypothyroidism . is. . higher. in . older. age groups and in whites and Hispanics; blacks had a lower prevalence of hypothyroidism. . The prevalence of hypothyroidism correlated with age. Compared with the total population, people aged 50 to 79 years had an almost twofold higher prevalence, and those aged 80 years and older had a fivefold higher prevalence. . Radiation Medical Science Center. . for the . Fukushima Health Management Survey,. Fukushima Medical University. The International Workshop on Radiation and Thyroid Cancer. Tetsuo Ishikawa. , Seiji . ghazal. Normal mass of thyroid about 30 g . Highly vascularized , receive about 120 ml blood / min .. Follicular cells secret : . Thyroxine. (. tetraiodothyronine. ) T4. Contains 4 ions of iodine . Thyroid rule:. In . a child, . critical for normal . growth and development. .. . In an adult, . maintain metabolic stability. . . Thyroid disorders result in . alterations in metabolic . stability. Shadi. . Haghi. M.D.. Research Institute for Endocrine Sciences. Shahid. . Beheshti. University of Medical sciences. 30 June 2014. AGENDA. A review on thyroid hormone treatment. (Endocrine 2013). Director, Chernobyl Tissue Bank . (. www.chernobyltissuebank.com. ). gerry.thomas@imperial.ac.uk. HEALTH . EFFECTS OF . NUCLEAR . POWER . INCIDENTS – WHERE CHEMISTRY AND PHYSICS COMBINE TO DRIVE BIOLOGY. Function Testing . Strategy. Clinical Details . Provided:. Tests Required:. Patient NOT on Thyroid . m. edication . OR. . Patient on T4. Patient . under . 18. OR. Patient . is pregnant . OR . Suspected/Known Pituitary disorder. Dr . Hiren. . Patt. D.M.. (Endocrinology). Myxoedema. Coma. What is . Myxoedema. Coma?. Severe hypothyroidism. Slowing of functions of multiple organs .