PPT-Basics of Genome Annotation

Daniel Standage Biology Department Indiana University Annota tion ˌa nə ˈ tā shən A critical or explanatory note or body of notes added to a text The act of annotating. Tao Huang, . Shrideep. . Pallickara. , Geoffrey Fox. Community Grids Lab. Indiana University, Bloomington. . {. taohuang. , . spallick. , . gcf}@indiana.edu. Outline. Analysis of existing Collaboration and Annotation Systems. BCB 660. October 20, 2011. From Carson Holt. Annotations. Automated. Ab. initio. (based on genomic sequence alone). Involves comparisons to known proteins (BLAST similarity). Sequence motifs such as start/stop . Massimo Poesio. University of . Essex. Part 1: Intro, . Microtask. . crowdsourcing. ANNOTATED CORPORA: . AN ERA OF PLENTY?. With the release of the . OntoNotes. and ANC corpora for English and a number of corpora for other languages (Prague Dependency Treebank especially) we may think we won’t need to do any more annotation for a while . &. Text Coding. Learning Target. I can determine a central idea of a text and how it is conveyed through particular details; provide a summary of the text distinct from personal opinions or judgments. . Abstract. A large number of organizations today generate and share textual descriptions of their products, services, and actions. Such collections of textual data contain significant amount of structured information, which remains buried in the unstructured text. While information extraction algorithms facilitate the extraction of structured relations, they are often expensive and inaccurate, especially when operating on top of text that does not contain any instances of the targeted structured information. . Philip . McParlane. , Yashar Moshfeghi and Joemon M. Jose. University of Glasgow, UK. http://www.dcs.gla.ac.uk/~philip/. p.mcparlane.1@research.gla.ac.uk. Motivation for annotating images. Problems with existing automatic image annotation collections. Thesis Proposal. Tao Huang. taohuang@cs.indiana.edu. Outline. Introduction. Motivation. Related System Survey. Research Issues. Milestones. Contributions. Introduction. Annotation Definitions. A commentary on an object that: (Cousins et al. 2000). A Close Reading Strategy for Better Comprehension. Text Annotation by Teachers. What is Text Annotation?. While reading, students mark the pages for . Important information. Text meaning or key details. Loralee Chevone-Garrett and Beth Dibble. ANNOTATION IS NOT. A coloring assignment. A detailed analysis. Exact or correct. Busy work. Teacher-centered. WHAT IS ANNOTATION?. RESEARCH SAYS.... A writing-to-learn strategy for use while reading and rereading.. Last Updated: 12/26/2021. Wilson Leung and Chris Shaffer. Agenda. Overview of the GEP annotation project. GEP annotation strategy. Types of evidence. Analysis tools. Web databases. Annotation of a single isoform (walkthrough). Lecture 3. Gene Finding and Sequence Annotation. Objectives of this lecture. Introduce you to basic concepts and approaches of gene finding. Show you differences between gene prediction for prokaryotic and eukaryotic genomes. HHMI Logistics. . Name badges must be worn at all times. Restrooms. No roaming through the building. Questions? – Ask . us. Refreshments . (keep to the schedule). Technology. Live Streaming. The microphones. a . Tool for Online Annotation and . Curation. Dorrie Main, Taein Lee, Ping . Zheng. , Sook Jung, Stephen P. Ficklin, Jodi Humann, . Jill . Wegrzyn.  and David Neale. What is . GenSAS. ?. It is a web-based . However, genomes are large and complex and visualizing this information is not easy. You need to imagine that the raw annotation information, by itself, can be contained in a text file, which could include positional information (coordinates relative to the reference genome) and different features (e.g. annotation type – gene, mRNA, intron/exon, variant, UTR, etc.).