PPT-Liver Metabolism of Drugs

By Aidan Cross and Tom Grant How many phases of drug metabolism are there 1 mark 3 Phases What is phase 1 of drug metabolism 2 Provide a functional group eg OH or NH 2 to increase polarity of the drug. Natalie . Craythorne. 27. th. September. . 2013. Aims for today. To know what a drug is and how they are classified. To understand where drugs come from. Be able to explain the “lock and key” and induced fit hypotheses. A. Metabolism. 1. Anabolism. A) synthesis reactions (building up). 2. Catabolism. A) lysis reactions (breaking down). B. Enzymes. 1. proteins that facilitate chemical reactions. Microbial Metabolism. MOVE Support . August 5, 2014. Glenna Stewart, MS RD LD. Energy Balance. Carbohydrate. . . Fat. Protein. Basal Metabolism. Physical Activity. Digestion, Absorption, & Processing Nutrients. GLYCOGEN . Found in liver and skeletal muscles.. Represents 10% of weight of liver and 1-2% of muscles.. Stored in large cytosolic granules.. Elementary particles, . β. -particles consist of 50,000 glucose residues.. A. Metabolism. 1. Anabolism. A) synthesis reactions (building up). 2. Catabolism. A) lysis reactions (breaking down). B. Enzymes. 1. proteins that facilitate chemical reactions. Microbial Metabolism. Dr Anissa Atif Mirza. What is Metabolism?. Metabolism is a . network of metabolic /biochemical reactions.. Carried out in living cells.. In a. well organized, integrated and regulated manner.. Related to various biomolecules viz. Department of Pharmaceutics. . . Drug metabolism or Biotransformation is the major mechanism for elimination of drug from the body.. . It is the process by which the drug is chemically modified . Dr Shaheen. Delivered By . Dr Naser . Drug interactions- objectives. Discuss Pharmacokinetic interactions. List . Pharmacodynamic. interactions. Comment . on common Drug- Food interactions. Drug interactions. Liver dysfunction and Drugs metabolism Dr V.Sebghatollahi Isfahan university of medical science Liver Functions: Metabolism – Carbohydrate, Fat & Protein Secretory – Bile acids, bile salts . . DR. . THINAKAR MANI . B . DM SENIOR RESIDENT. INSTITUTE OF MEDICAL GASTROENTEROLOGY . MADRAS MEDICAL COLLEGE. . CHENNAI,TAMILNADU. “Precision medicine for healthy aging”. WORKSHOP 4. Hepato-Gastroenterology/Lipids . ORGANIZERS. Dr. Piero Portincasa (UNIBA, Bari, . Italy. ). Dr. Matías Ávila (UNAV, Pamplona, . Spain. ) . Thursday 31. Download PDF Fatty Liver Remedy™ eBook by Layla Jeffrey - a comprehensive guide designed to address and alleviate the symptoms of fatty liver disease through natural and lifestyle-based approaches. Download PDF The Fatty Liver Solution™ eBook by Duncan Capicchiano - A natural and effective approach to tackling fatty liver disease. DILI. Prepared by:. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). Objectives :. At the end of this lecture, the student should know:. What is DILI?. What are the different pattern of DILI?.