PPT-Jaundice: Causes and Etiopathogenesis

Dr Ashok Singh Assistant Professor Dept of Pathology INTEGRATED TEACHING Jaune Yellow पलय Icterus Latin Sighting the bird was thought to cure jaundice Jaundice. Outbreaks of jaundice probably hepatitis A were reported in the 17th and 18th centuries particularly in association with military campaigns Hepatitis A formerly called infectious hepatitis was first differentiated epidemiologically from hepatitis B Conclusions . . * . Jaundice indicates that there is an elevated concentration of bilirubin in serum.. * In neonates it is important to determine the concentration of unconjugated bilirubin in order to decide what treatment is required.. . Dr. Ravi Kant. Assistant Professor. Department of General Medicine. Introduction. Jaundice or . icterus. , is a yellowish discoloration of tissue resulting from the deposition of . bilirubin. .. Tissue deposition of bilirubin occurs only in the presence of serum . Pediatric Continuity Clinic Curriculum. Onyekachukwu Osakwe. Objectives. Recognize the common findings in newborns with . hyperbilirubinemia. . . Describe bilirubin metabolism. Distinguish between direct and indirect . Assist.Lecturer. Aseel. . Ghassan. . Daoud. M.Sc. in Pharmacy/Clinical . L. aboratory . S. ciences. What is bilirubin?. It is a brownish yellow substance found in bile and it is produced during the breakdown of old RBCs then removed from the body through feces.. Objectives. Understand etiology and pathophysiology of neonatal jaundice and kernicterus. Identify high risk conditions. Understand limits of clinical exam. Describe appropriate evaluation. Apply appropriate treatment to term and near term infants. Dr.S.Parthasarathy. . MD DA . DNB. PhD FICA IDRA . Anatomy . Functions of liver . The liver is vital for. protein synthesis. glucose homeostasis . . bilirubin. excretion . toxin removal . Dr. Vivek Kr. Singh . Assistant Professor. Department of Veterinary Clinical Complex . UNIT-2. Jaundice is also referred to as . icterus,. and is an important . clinical manifestation. to . liver diseases and biliary system. Rob Grogan . rjg17@ic.ac.uk. . Year 4 BSc Anaesthesia & Crit Care. Disclaimer & sponsor . “. MedED. does not represent the ICSM Faculty or Student Union. This lecture series has been designed and produced by students. We have made every effort to ensure that the information contained is accurate and in line with Learning Objectives featured on SOFIA, however, this guide should not be used to replace formal ICSM teaching and educational materials.”. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). At the end of this lecture , you must be able to answer these questions. Q1:. 22 year old male patient , with history of recurrent self resolving jaundice since childhood, presented with jaundice at the end of heavy duty day , otherwise the patient is healthy with nonsignificant other finding,. Rashidy. Lecturer of General and Pediatric Surgery. Jaundice. Yellowish discoloration of body tissues & fluids (except the brain, CSF, tears, saliva & milk) due to excess . bilirubin. in the blood.. Asst.professor. paediatrics. What is the Neonatal Jaundice?. Neonatal Jaundice(also called Newborn jaundice) is a condition marked . by high levels of bilirubin in the blood. . . The increased bilirubin cause the infant's skin and whites of the eyes (sclera) to look yellow.. Normal TSB (0.5-1.5mg). Jaundice . is usually detectable clinically when the plasma bilirubin. exceeds 40 . μmol. /L (~2.5 mg/. dL. ).. Bilirubin in the blood is normally almost all unconjugated and,. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). Objectives:. At end of this lecture, the student should know :. 1.What is jaundice ?. 2. Types of jaundice?. 3. How you approach to each type of jaundice?. Jaundice.