PPT-Physiological acid base balance

This lecture presents the basic concepts of pharmaceutical inorganic chemistry with emphasis on the description mechanisms and uses of various pharmaceutical products which are clinically used to correct various body disorders The major topics to be covered are acids and bases intra and extra cellular electrolytes the gastrointestinal agents and topical agents frequently employed in the conversion of drugs to chemical forms convenient to their product formulations. Titration. Acid–Base Titration. The concentration of a weak acid or a weak base in water is difficult – if not impossible – to measure directly.. But we can calculate the concentration from the results of titration.. of Salts. Acid-Base Properties of Salts. Type of Salt. Examples. Comment. pH of solution. Cation is from a strong base, anion from a strong acid. KCl, KNO. 3. NaCl. NaNO. 3. Both ions are neutral. Neutral. Fluid, Electrolyte, and Acid-Base Balance. 1. Body Water Content. Infants have low body fat, low bone mass, and are 73% or more water. Total water content declines throughout life. Healthy males are about 60% water; healthy females are around 50%. Lecture Presentation. James F. Kirby. Quinnipiac University. Hamden, CT. © 20. 15. Pearson Education, Inc.. 16.1 & 16.2 Some . Definitions. Arrhenius. An acid is a substance that, when dissolved in water, increases the concentration of hydrogen ions.. 2009, Prentice-Hall, Inc.. Titration. In . this technique a known concentration of base (or acid) is slowly added to a solution of acid (or base. ).. The . analyte. - is the solutions being evaluated and is of unknown concentration.. Coakley. 2/27/2014. Quick Review: Acids. Acids are compounds which function as. hydrogen (H+) donors . in biochemical equations/solutes. The more free H+ ions available for donation, the more acidic the compound. M. . Gardner. Copyright2/4/2013. ACID /BASE BALANCE. In order to meet homeostasis, the body fluids must maintain a stable chemical balance of hydrogen ions in body fluids.. This is done by regulating their acidity /alkalinity. . Learning Objectives. Describe . what is meant by acids, bases and . buffers. List . normal pH of the body fluids. . Describe . the processes involved in maintenance of normal blood pH. .. Describe . various types of acidosis and alkalosis. For cells to function optimally, . a steady balance . between the acids and the bases . is necessary.. Acid-base balance represents homeostasis of hydrogen (H+) ion . concentration in . body fluids. . Pah. enu2. Mice. Relevance to PKU Therapy. Mike Gibson, Professor and Head. Section of Clinical Pharmacology. Washington State University (WSU) Spokane. College of Pharmacy, Spokane WA . Disclosures: None. Schedule. Intro. Why the pH value of body fluids must be “defended”. Defining pH. Logarithms . (see appendix). Acidosis and alkalosis. Biological Buffers and the Henderson-. Hasselbalch. equation. Acid-base balance.  . * Acids are electrolytes that release hydrogen ions (H+) when they are dissolved in water.. * Bases are electrolytes are release hydroxide ions (OH-) when they are dissolved in water.. Download PDF Acid Reflux Solution Kit™ eBook by Barton - a comprehensive step-by-step system designed to treat acid reflux and heartburn issues naturally. Acid. is defined as a substance which when dissolved in water gives hydrogen ions. (H +) . Examples.. Base is defined as a substance which when dissolved in water gives hydroxyl ions. (OH-) . Examples..