PPT-Eukaryotic Gene Regulation

5 mechanisms Chromatin Structure Transcriptional Posttranscriptional Translational Posttranslational Chromatin Structure Which of these is more accessible to the kitten A Or B Figure 157. 7. 7 RNA Synthesis and Processing. Chapter Outline. Transcription in Prokaryotes. Eukaryotic RNA Polymerases and General Transcription Factors. Regulation of Transcription in Eukaryotes. RNA Processing and Turnover. Eukaryotic Gene Regulation. How are genes turned on & off . in eukaryotes?. How do cells with the same genes differentiate to perform completely different, specialized functions?. Evolution of gene regulation. Gene Expression Group. 7/14/11. 2011 National Academies Northstar Institute for Undergraduate Education in Biology . Outline. Context. Review: Clicker Questions. Cell Differences (Think-Pair-Share). Regulation of Gene Expression (Mini-Lecture). Pre-transcriptional regulation. chromatin compaction . eg. . deacetylation. , . methylation. transcriptional initiation . ie. transcription factors to activate or repress. alternative promoters =. Structure dictates function . Prokaryotic transcription is simpler. DNA exists in one chromosome . Less non-coding sequence. RNA polymerase binds the promoter directly. Genes are clustered into functional groups called operons. CSCOPE. Unit: 08 Lesson: 01. There are hundreds of different types of cells in your body, and each type has a unique function. We’re going to compare some different types of cells to see how much they have in common. . Draw 8 boxes on your paper. Gene regulation accounts for some of the phenotypic differences between organisms with similar genes.. 2005-2006. Gene regulation in bacteria. Control of gene expression enables individual bacteria to adjust their metabolism to environmental change. The cerebellum is the region of the brain that coordinates motor control, and many human neural disorders impact the cerebellum.. Several spontaneous mouse mutants with motor defects have been found, including:. Gene Regulation Gene expression can be turned on, turned off, turned up or turned down! For example, as test time approaches, some of you may note that stomach acid production increases dramatically&# (Chapter 9). Presented by Dr. Laurie M. Erickson. Chair of the Department of Health Sciences. Blitstein Institute of Hebrew Theological College. Chicago, IL, USA.. Gene Expression can be Regulated.. Gene expression: . Definition:. Anything genetic above and beyond the . sequence. of nucleotides. Importance:. Everything. , especially development and genetic. responses to the environment.. Examples of Epigenesis:. 1) Development: tissue differentiation and timing. &. RNA structure and functions . Lec. 7. th. Molecular biology . Expression of essential genes is required under all growth conditions but the expression of other genes is conditional. Thus, cells must regulate gene expression using transcription regulation to determine which genes are transcribed and to what extent. Transcription regulation is the most common mechanism to control gene expression in bacteria. AP Bio – Ch. 16-21. Unit 6 – Overview. Ch. 16 – The Molecular Basis of Inheritance (DNA). Ch. 17 – Gene Expression: From Gene to Protein. Ch. 18 – Regulation of Gene Expression. Ch. . 19 . – . A single guiding RNA (sgRNA; . a fusion of . tracrRNA. and crRNA. ) . binds CAS9 protein at one end, the other end guides CAS9 to target DNA sequence based on complementarity. . Gene for the CAS9 protein, encodes endonuclease, cuts both strands of the target sequence.